Research Masterclass in Radiotherapy Physics 2017

Tissue changes in MRI post RT: Craniospinal pRT Treatment planning CT and dose T1-w MRI 6 months after pRT

HIT patient

Page 25 Changes in fat signal in irradiated part of vertebral bodies, Distal dose fall off can be visualized – how early ?? Described already in Krejcarek, Yock, et al. IJROBP 2007;68(3):646-649 Oliver Jäkel Medical Physics

MRI for response assessment during p-RT?

Planning CT

Post 3fx

Difference Image (Post 5fx - Post 3fx)

Post 5fx

Dose-correlated changes visible about 10-12 days after start of treatment!

C Richter et al. Med. Hypoth. 2014

Oliver Jäkel Not in all patients though – to be investigated Medical Physics

Page 26

Made with FlippingBook Annual report