Research Masterclass in Radiotherapy Physics 2017

Major trends and research opportunities in predictive modelling with relevant contribution from MP: Normal tissues

 Incorporation of clinical and «omics» predictors into dose-volume (phenomenological) models: methods for variable selection, robustness assessment, validation  Data-sharing and data- mining issues  Objective, image-based scoring of toxicity

 Involvement into data analysis/modelling of clinical trials/Institutional series  Overcoming organ-based approach of dose-volume modelling (considering the 3D dose distribution, similarity/dissimilarity comparisons, multi-structure models…)  Incorporation of delivered dose into models (replacing planned doses)

(morphological and functional changes)