1890 Coca and its Therapeutic Application by Angelo Mariani

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wine, which serves as a vehicle, exciting the vitality of each organ separately, not, however, without having pre viously exerted its vivifying action on the mucous mem brane of the stomach itself." {^Gazette dcs Hopitaux, Nov. 23,1877.) The analgesic properties of Vin Mariani have received a happy application in clinical laryngoscopy by Dr.Ch. Fau- vel. This eminent specialist has made use of it for the past twenty-six years with unvarying success in all affec tions of the laryngeal mucous membrane,the air passages, and the vocal organs. In granular angina ittakesthe place of the topical medication and cauterizations which are so often injurious when they are used indiscriminately and to excess. The employment of Vin Mariani rapidly relieves pa tients of the feeling of heat and tingling which is one of the most annoying symptoms of this very com mon disease of the throat. {Gazette des Hopitaux, May 12, 1877.) Dr. Beverley Robinson recommends Vin Mariani as a heart tonic. Dr.W.H.Pancoast says that Vin Mariani is a valuable preparation and a tonic of the highest merit. Dr. Jules Bouvyer,of Cauteretz,employs it with success in certain affections of the larynx as an adjuvant to the sulphurous treatment. In1875,in his Traiteinent rationnel de la phtJasie pulmonatre. Dr.de Pietra Santa said, page 894: "Among the mostrenowned practitioners of Paris,P^an, Barth,G.S6e,and Cabrol have promptly adopted the prep arations of Coca. Ch.Fauvel prescribes it in affections of the respiratory passages. It is in these diseases that I,too, have had occasion to advise its daily use in the most con venient,the most agreeable,and the most activeform—that of the Vin Tonique de MarianiV Thus has been realized Reveil's prediction:"This sub-

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