Biophysical Society 62nd Annual Meeting | Program Guide

2750-Symp 1:30 pm KINESIN MOTOR DOMAIN DYNAMICS DURING SINGLE-MOTOR STEPPING AND MULTI-MOTOR TRANSPORT. William O. Hancock 2752-Symp 2:30 pm ONE MOTOR, MANY FUNCTIONS: LOCALIZED REGULATION OF CYTOPLAS- MIC DYNEIN IN NEURONS BY EFFECTOR PROTEINS.  Erika Holzbaur Symposium New and Notable 1:00 pm–3:00 pm, South Lobby, South, Level Two, Room 297/208 Co-Chairs Anne Kenworthy, Vanderbilt University School of Medicine Francesca Marassi, Sanford Burnham Prebys medical Discovery Institute No Abstract 1:00 pm ULTRAFAST GLUTAMATE SENSORS RESOLVE SYNAPTIC SHORT-TERM PLAS- TICITY. Katalin Torok No Abstract 1:20 pm THE DYNAMIC ORGANIZATION OF MODIFIED CHROMATIN FIBERS RE- VEALED BY SINGLE-MOLECULE FRET. Beat Fierz No Abstract 1:40 pm FUNDAMENTAL TRADE-OFFS BETWEEN INFORMATION FLOWIN SINGLE CELLS AND CELLULAR POPULATIONS. Eric J. Deeds  No Abstract 2:00 pm NEW TOOLS AND TECHNIQUES FOR MEASURING AND MANIPULATING CHAIN COLLAPSE IN INTRINSICALLY DISORDERED PROTEINS. Patricia L. Clark No Abstract 2:20 pm STRUCTURE OF THE COLD AND MENTHOL SENSOR TRPM8.   Seok-Yong Lee No Abstract 2:40 pm INTEGRATING X-RAY SCATTERING INTO PROTEINSTRUCTURE PREDICTION. Susan Tsutakawa Platform Molecular Dynamics II 1:00 pm–3:00 pm, South, Level Two, Room 215/216 Co-Chairs Albert Pan, D.E. Shaw Research Lukas Stelzl, University of Oxford, United Kingdom 2753-Plat 1:00 pm SIMULATION OF GEOMETRICALLY ACCURATE, MULTIBILLION ATOM CEL- LULAR MEMBRANE STRUCTURES. Noah Trebesch , Emad Tajkhorshid 2754-Plat 1:15 pm COMPUTATIONAL HIGH-THROUGHPUT SCREENING OF DRUG-MEM- BRANE THERMODYNAMICS.  Tristan Bereau 2755-Plat 1:30 pm ATOMIC-LEVEL CHARACTERIZATION OF PROTEIN-PROTEIN ASSOCIATION.  Albert C. Pan , Daniel Jacobson, Konstantin Borisov, Duluxan Sritharan, Thomas M. Weinreich, David E. Shaw 2756-Plat 1:45 pm A MINIMAL COARSE-GRAINED MOLECULAR DYNAMICS MODEL OF AXON PLASMA MEMBRANE WITH ITS IMPLICATION ON THE DIFFUSION BEHAV- IOR OF AXON MEMBRANE PROTEINS.  Yihao Zhang , George Lykotrafitis

2757-Plat 2:00 pm DYNAMIC HISTOGRAM ANALYSIS TO DETERMINE FREE ENERGIES AND RATES FROM BIASED SIMULATIONS.  Lukas S. Stelzl , Adam Kells, Edina Rosta, Gerhard Hummer 2758-Plat 2:15 pm WEIGHTED ENSEMBLE SIMULATION STUDIES OF MILLISECOND FOLDER NTL9.  Upendra Adhikari , Barmak Mostofian, Daniel M. Zuckerman 2759-Plat 2:30 pm ENHANCED SAMPLING AND BAYESIAN INFERENCE TO MODEL THE CON- FORMATIONAL DYNAMICS OF PEPTOID MACROCYCLES.  Matthew Hurley , JD Northrup, Vincent Voelz, Chris Schafmeister 2760-Plat 2:45 pm TOWARDS DYNAMIC PHARMACOPHORE MODELS BY COARSE GRAINED MOLECULAR DYNAMICS.  Nicholas Michelarakis , Zara A. Sands, Mark S.P. Sansom, Phillip J. Stansfeld Platform CONFORMATIONAL LANDSCAPE OF SODIUM GLUCOSE TRANSPORTERS.  Paola Bisignano , Sara Capponi, John M. Rosenberg, Michael Grabe 2762-Plat 1:15 pm SINGLE-MOLECULE ANALYSIS OF PHOSPHOLIPID SCRAMBLING BY TMEM16F.  Rikiya Watanabe , Takaharu Sakuragi, Hiroyuki Noji, Shigekazu Nagata 2763-Plat 1:30 pm MEASURING MEMBRANE SURFACE REACTIONS BY DIFFUSION: DIMER- IZATION OF BTK PH DOMAIN AND K-RAS.  Jean K. Chung , Laura M. Nocka, Young Kwang Lee, John Kuriyan, Jay T. Groves 2764-Plat 1:45 pm A COMBINED SIMULATION AND SAXS STUDY OF THE DYNAMICS OF LIPID NANODISCS.  Tone Bengtsen , Viktor L. Holm, Søren R. Midtgaard, Lise Arleth, Kresten Lindorff-Larsen 2765-Plat 2:00 pm EFFECT OF THE ENDOSOMAL ACIDIFICATION ON SMALL ION TRANSPORT THROUGH THE ANTHRAX TOXIN PA 63 CHANNEL.  Nnanya Kalu, Antonio Alcaraz, Goli Yamini, Sanaz Momben Abolfath, Laura Lucas, Clare Kenney, Vicente M. Aguilella, Ekaterina M. Nestorovich 2766-Plat 2:15 pm COMBINED HIGH-SPEED SINGLE PARTICLE TRACKING OF MEMBRANE PROTEINS AND SUPERRESOLUTION OF MEMBRANE-ASSOCIATED STRUC- TURES.  Hanieh Mazloom-Farsibaf , Keith Lidke 2767-Plat 2:30 pm EXAMINING LENGTH AND CHARGE DISTRIBUTION OF THE PERIPLASMIC N-TAIL OF BITOPIC MODEL PROTEINS AS DETERMINANTS OF ITS YIDC AND SEC REQUIREMENT IN E.COLI .  Sri Karthika Shanmugam , Ross E. Dalbey 2768-Plat 2:45 pm DYNAMICS OF P-TYPE ATPASE TRANSPORT CYCLE REVEALED BY SINGLE- MOLECULE FRET. Mateusz Dyla , Daniel S. Terry, Magnus Kjaergaard, Thomas L-M Sørensen, Jacob Lauwring Andersen, Jens Peter Ander- sen, Charlotte Rohde Knudsen, Roger B. Altman, Poul Nissen, Scott C. Blanchard Membrane Protein Dynamics 1:00 pm–3:00 pm, Esplanade, Room 153 Co-Chairs Ekaterina Nestorovich, The Catholic University of america Paola Bisignano, University of California, San Francisco 2761-Plat 1:00 pm

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