Biophysical Society 62nd Annual Meeting | Program Guide

466-Pos Board B236 HIGH-RESOLUTION SINGLE-MOLECULE ANALYSIS OF UVRD HELICASE US- ING NANOPORE TWEEZERS. Hugh Higinbotham 467-Pos Board B237 ANALYSIS OF FORCE DEPENDENCE OF TRANSLOCATION AND UNWIND- ING OF HELICASE PCRA USING SPRNT. Andrew H. Laszlo , Jonathan M. Craig, Henry Brinkerhoff, Ian C. Nova, Matthew T. Noakes, Jonathan W. Mount, Jasmine O. Bowman, Hugh Higinbotham, Katherine Baker, Jesse Huang, Ramreddy Tippana, Momcilo Gavrilov, Taekjip Ha, Jens H. Gundlach 468-Pos Board B238 REGULATION OF A VIRAL PACKAGING MOTOR’S GRIP ON DNA.  Mariam Ordyan , Douglas E. Smith, Venigalla B. Rao, Istiaq Alam, Mar- thandan Mahalingam 469-Pos Board B239 CHALLENGING A DNA PACKAGING MOTOR WITH A MODIFIED SUB- STRATE.  Juan P. Castillo , Alexander Tong, Sara Tafoya, Paul Jardine, Carlos Bustamante 470-Pos Board B240 CONSTRUCTION OF A VIRAL HELICASE NANOPORE FOR ACTIVE DNA UN- WINDING AND TRANSPORT. Yuejia Chen , Ke Sun, Changjian Zhao, Xialin Zhang, Jia Geng 471-Pos Board B241 MEASURING SEARCH TIMES IN SITE SPECIFIC DNA BINDING.  Allen C. Price , Raquel Ferreira, Sadie Piatt, Stephen Parziale 472-Pos Board B242 SINGLE MOLECULE DETECTION OF TRANSCRIPTION FACTOR USING FLUO- RESCENT MOLECULAR BEACONS. Pin Ren , Yuji Ishitsuka, Paul Selvin 473-Pos Board B243 SHORT-READ SINGLE-MOLECULE DNA SEQUENCING FOR HIGHLY PARAL- LEL ANALYSIS OF PROTEIN-DNA INTERACTIONS. Rebecca Andrews , Horst Steuer, Arun Shivalingam, Afaf H. El-Sagheer, Tom Brown, Achillefs N. Kapanidis 474-Pos Board B244 DIRECT AFM VISUALIZATION OF RECG TRANSLOCATION AFTER REMODEL- ING BY SSB PROTEIN. Zhiqiang Sun , Mohtadin Hashemi1, Piero R. Bianco, Yuri L. Lyubchenko 475-Pos Board B245 PEAKFORCE TAPPING AFM REVEALS THAT HUMAN XPA BINDS TO DNA DAMAGE AS A MONOMER PRODUCING A 60° BEND. Emily C. Beckwitt , Nina Simon, Isadora Carnaval, Caroline Kisker, Thomas Carell, Bennett Van Board B246 ENERGETICS OF NUCLEOTIDE TRANSLOCATION THROUGH HIV-1 CA HEX- AMER. Chaoyi Xu , Juan Perilla 477-Pos Board B247 CHARACTERIZATION OF SINGLE-STRANDED DNA BINDING BY APOBEC3 FAMILY PROTEINS USING FORCE SPECTROSCOPY. Michael Morse , Yuqing Feng, Robin P. Love, Ioulia Rouzina, Linda Chelico, Mark C. Williams 478-Pos Board B248 RNA POLYMERASE PAUSES AT LAC REPRESSOR OBSTACLES. Yan Yan , Wenxuan Xu, David D. Dunlap, Laura Finzi Houten 476-Pos

454-Pos Board B224 IMPROVED SAMPLING IN MOLECULAR DYNAMIC STUDIES OF Z[WC]-DNA AND THE B TO Z-DNA TRANSITION. Sirajus Salekin , Micaela Bush, Alma Gracic, Ahmed Imamovic, Ahsan A. Khoja, Jinhee Kim, Lam T. Nguyen, Sunil Pun, Ashutosh Rai, Sirajus Salekin, Alexander K. Seewald, Benjamin L. Yee, Michael G. Lerner 455-Pos Board B225 DETERMINING THE EFFECTS OF METHYLATION ON THE FLEXIBILITY OF CGG/CCG REPEAT DNA. Michaela Norbury , Catherine Volle 456-Pos Board B226 DNA HYBRIDIZATION: CONCENTRATION-DEPENDENT CHANGES IN BIND- ING AFFINITY REVEAL INTRINSIC CHANGE IN HYDRATION ENERGY. Caro- line Harmon, Juan Rangel, Christopher Trinh, Daryl K. Eggers 457-Pos Board B227 A COARSE-GRAINED SIMULATION STUDY OF THE EFFECT OF SALT CON- CENTRATION ON DNA INTERNAL MOTIONS. Benson Ma , Edmond Chow 458-Pos Board B228 QUANTIFYING NUCLEIC ACID BASE PAIRING FREE ENERGY. Rongpeng Li , Chi H. Mak 459-Pos Board B229 BINDING KINETICS OF DNA INTERCALATION BY SMALL RHODIUM COM- PLEXES. Guðfríður Björg Möller , Liam Price, Grace Ferris, Micah J. McCau- ley, Ioulia Rouzina, Megan Nú ez, Mark C. Williams 459.1-Pos Board B229.1 HYPERSTRETCHING DNA. Koen Schakenraad, Andreas S. Biebricher, Maarten Sebregts, Brian ten Bensel, Erwin J.G. Peterman, Gijs J.L. Wuite, Cornelis Storm, Paul van der Schoot, Paul van der Schoot, Iddo Heller Protein-Nucleic Acid Interactions I (Boards B230–B248) 460-Pos Board B230 A NANOFLUIDIC DEVICE FOR REAL-TIME VISUALIZATION OF DNA-PRO- TEIN INTERACTIONS ON THE SINGLE DNA MOLECULE LEVEL. Robin Öz , Sriram Kesarimangalam Kalyanavenkatramanan, Fredrik Westerlund 461-Pos Board B231 INTERACTIONS BETWEEN THE BACTERIOPHAGE PROTEIN COX AND DNA INVESTIGATED ON THE SINGLE DNA MOLECULE LEVEL USING NANOFLU- IDIC CHANNELS. Karolin Frykholm, Ronnie P-A Berntsson, Pål Stenmark, Fredrik Westerlund 462-Pos Board B232 INTERACTIONS BETWEEN DNA AND HIV-1 NUCLEOCAPSID PROTEIN STUDIED USING NANOFLUIDIC CHANNELS. Kai Jiang , Nicolas Humbert, Sriram Kesarimangalam Kalyanavenkatramanan, Yves Mely, Fredrik Westerlund 463-Pos Board B233 DESIGN OF NOVEL MAGNETIC TWEEZERS AND ITS USE FOR STUDYING DNA-COMPACTING PROTEINS. Roberto Jr Fabian , Christopher Tyson, Anneliese Striz, Pamela L. Tuma, Ian L. Pegg, Abhijit Sarkar 464-Pos Board B234 International Travel Awardee LATERAL MAGNETIC TWEEZERS TO STUDY DNA:PROTEIN INTERAC- TIONS.  Julene Madariaga-Marcos , Silvia Horme o, Cesar L. Pastrana, Gemma L. M. Fisher, Mark S. Dillingham, Fernando Moreno-Herrero 465-Pos Board B235 MECHANISM OF SEQUENCE DEPENDENT TRANSLOCATION OF A SUPER- FAMILY 2 HELICASE ON SSDNA.  Jonathan M. Craig

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