Biophysical Society 62nd Annual Meeting | Program Guide

997-Plat 11:00 am CHOLESTEROL AND NEUROSTEROIDS BIND COMMON SITES BUT ASSUME DIFFERENT ORIENTATIONS IN A PENTAMERIC LIGAND GATED ION CHAN- NEL. Melissa M. Budelier , Wayland W. L. Cheng, John R. Bracamontes, Zi-Wei Chen, Krishnan Kathiresan, Laurel Mydock-McGrane, Douglas F. Covey, Alex S. Evers 998-Plat 11:15 am PROTEIN-LIPID INTERACTIONS ON THE HIV MEMBRANE DEFINED BY EPR SPECTROSCOPY.  Likai Song , Zahra Hayati, Mengtian Liu, Mikyung Kim, Ellis Reinherz 999-Plat 11:30 am CPOW Travel Awardee STRUCTURAL PLASTICITY OF THE PIVOTAL CYTOCHROME C/CARDIO- LIPIN COMPLEX IN MITOCHONDRIAL APOPTOSIS. Mingyue Li , Abhishek Mandal, Maria DeLucia, Jinwoo Ahn, Vladimir A. Tyurin, Valerian E. Kagan, Patrick C.A. van der Wel 1000-Plat 11:45 am CYTOCHROME P450 / CYTOCHROME P450 REDUCTASE COMPLEX FORMATION DEPENDS ON NADPH: A SINGLE PROTEIN TRACKING STUDY.  James A. Brozik , Carlo Barnaba, Evan Taylor 1001-Plat 12:00 pm CAVEOLIN-ASSISTED SPHINGOLIPID TRANSPORT TO THE PLASMA MEM- BRANE.  Joanna Podkalicka , Manuela Dezi, John Manzi, Aurelie Di Cicco, Daniel Levy, Christophe Lamaze, Patricia Bassereau 1002-Plat 12:15 pm GRAMICIDIN INCREASES LIPID FLIP-FLOP IN SYMMETRIC AND ASYM- METRIC LIPID VESICLES. Milka Doktorova , Frederick A. Heberle, Drew Marquardt, Radda Rusinova, Lea Sanford, Thasin Peyear, John Katsaras, Gerald Feigenson, Olaf S. Andersen 1003-Plat 12:30 pm MAPPING THE INTERACTIONS OF ALPHA-SYNUCLEIN TO LIPID MEM- BRANES IN THE PHYSIOLOGICAL LIMIT.  Peter J. Chung , Hyeondo Hwang, Alessandra Leong, Erin J. Adams, Ka Yee C. Lee Platform Protein Folding, Stability, and Evolution 10:45 am–12:45 pm, Esplanade, Room 153 Co-Chairs Kresten Lindorff-Larsen, University of Copenhagen, Denmark Yuning Hong, La Trobe University, Australia 1004-Plat 10:45 am PREDICTION OF CHANGES IN PROTEIN FOLDING STABILITY UPON SINGLE RESIDUE MUTATIONS.  Carlos A. Bueno , Davit A. Potoyan, Ryan R. Cheng, Peter G. Wolynes 1005-Plat 11:00 am TOWARDS IMPROVED BIOPHYSICAL CALCULATIONS TO IDENTIFY DISEASE-CAUSING MUTATIONS.  Kresten Lindorff-Larsen , Amelie Stein, Kaare Teilum, Alex Toftgaard Nielsen, Rasmus Hartmann-Petersen 1006-Plat 11:15 am International Travel Awardee MUTANT PHENOTYPE PREDICTION AND PROTEIN MODEL DISCRIMINA- TION USING DEEP SEQUENCING DATA.  Shruti Khare , Kritika Gupta, Arti Tripathi 1007-Plat 11:30 am THE PHYSICAL ORIGINS OF ENZYME EVOLUTION: CORRELATING THE AC- TIVE SITE ELECTRIC FIELDS OF ANTIBIOTIC RESISTANCE ALONG EVOLU- TIONARY TRAJECTORIES IN TEM Β-LACTAMASES.  Samuel H. Schneider , Jacek A. Kozuch, Steven G. Boxer

990-Symp 11:45 am TRANS-SYNAPTIC PROTEIN ORGANIZATION ALIGNING VESICLE FUSION WITH RECEPTORS.  Thomas Blanpied 991-Symp 12:15 pm VISUALIZING MEMBRANE STRUCTURAL REMODELING DURING FUSION AND FISSION IN LIVE CELLS.  Ling-Gang Wu Symposium Cardiac Contractility 10:45 am–12:45 pm, North, Lower Lobby, Room 25 Co-Chairs Livia Hool, University of Western Australia Brian Sykes, University of Alberta, Canada 992-Symp 10:45 am ELUCIDATING THE MOLECULAR MECHANISMS FOR ACTIVATION OF THE L-TYPE CALCIUM CHANNEL IN THE FIGHT OR FLIGHT RESPONSE.  Livia C. Hool 993-Symp 11:15 am IS THE HEART DRUGGABLE? DEVELOPMENT OF A CALCIUM SENSITIZER.  Brian Sykes 994-Symp 11:45 am SPECTROSCOPIC PROBES OF CARDIAC CONTRACTILITY AND THERAPEU- TIC DISCOVERY.  David Dale Thomas 995-Symp 12:15 pm POST-TRANSLATIONAL MODIFICATION SIGNALING AND BIOELECTRICAL, BIOPHYSICAL AND BIOENERGETIC PACEMAKER FUNCTION.  Yael Yaniv Symposium Future of Biophysics 10:45 am–12:45 pm, South, Level Two, Room 207/208 Support contributed by the Burroughs Wellcome Fund Co-Chairs Anne Kenworthy, Vanderbilt University Francesca Marassi, Sanford Burnham Prebys Medical Discovery Institute No Abstract 10:45 am THE INVISIBLE DANCE OF CRISPR-CAS9.  Giulia Palermo No Abstract 11:15 am CONFORMATIONAL AND FUNCTIONAL FLEXIBILITY OF THE MOLECULAR CHAPERONE BIP.  Anastasia Zhuravleva No Abstract 11:45 am PUSHING THE ENVELOPE: TOWARD A NANOSCALE MODEL OF HIV-1 AS- SEMBLY.  Schuyler Van Engelenburg No Abstract 12:15 pm NEW STRUCTURE-ACTIVITY PARADIGMS FOR amYLOIDS FROM PATHO- GENIC MICROBES. Meytal Landau Platform Protein-Lipid Interactions II 10:45 am–12:45 pm, South, Level Two, Room 215/216 Co-Chairs Michael Brown, University of Arizona Carmen Domene, King’s College London, United Kingdom 996-Plat 10:45 am MOLECULAR RECOGNITION AT THE MEMBRANE INTERFACE: PROTEIN- MEMBRANE ELECTROSTATIC INTERACTIONS MODULATE THE BIOLOGICAL FUNCTION OF ANTI-HIV ANTIBODIES.  Jose L. Nieva , Edurne Rujas, Sara Insausti, Daniel P. Leaman, Beatriz Apellaniz, Johana Torralba, Lei Zhang, Jose M. Caaveiro, Michael B. Zwick

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