Amino Acids Working Group Meeting Book (November 28, 2017)

Amino Acids Working Group Spreadsheet Info. 11-28-17

Should be in SMPR

Proposed change of SMPR

Guideline

Conc. [mg/100g]

Conc. [g/100g]

RSD(H)*[%]

RSD(R)**[%]

RSD(r)***[%]

'RSD(R)

'RSD(r)

Concentration %

or

Conc. [mg/100g]

Low High Medium Medium

Equivilent

'RSD(R)

'RSD(r)

'RSD(r)

Range 0.4‐5

Low High

Low High

Low High

Low High

11

7 5 3

0.001

11

7.3 5.3 3.7

7 5 4

0.4

5 0.0004 0.005

12.99

8.88 6.28 3.48

8.44 5.77 4.08

5.77 4.08 2.27

6.49 4.44 3.14

4.44 3.14 1.74

8 5

0.01

8 6

5‐50

5

50 0.005

0.05

8.88 6.28

0.1

50‐2500

50 2500

0.05

2.5

* Harwitz formula calculated predicting RSD for reproducibility ** RSD of reproducibility obtained by 2 times of RSD(H). *** RSD of repeatability obtained by 1.3 times of 'RSD(R)H