Special Edition of Prescrire International

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Editorial - Antibiotics : no market, no interest 4
NEW PRODUCTS5
Dupilumab - Dupixent°. In adults with atopic dermatitis 5
Midostaurin - Rydapt°. For some types of acute myeloid leukaemia6
Pembrolizumab - Keytruda°. In urothelial carcinoma7
SC tocilizumab - RoActemra° In giant cell arteritis 8
Cladribine : insufficient clinical benefit in multiple sclerosis 10
ADVERSE EFFECTS11
Methylphenidate during pregnancy11
Gabapentin and pregabalin : death reported13
Silver sulfadiazine cream : disportionate adverse effects14
REVIEWS15
Stable angina and antithrombotic drugs 15
Minor ischaemic stroke and antiplatelet drugs16
OUTLOOK17
Drugs in 2018 : a brief review 17
Publicly-funded research : too opaque!20
Toward better patient care : drugs to avoid in 201921

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