ESTRO Brachytherapy for Prostate Cancer 2018

High-resolution genome-wide single nucleotide polymorphism and copy number survey

Non metastatic

Metastatic / non lethal

Metastatic / lethal

“D espite common genomic heterogeneity in primary cancers, most metastatic cancers arise from a single precursor cancer cell.”

Liu W, Laitinen S, Khan S, Vihinen M, Kowalski J, Yu G, Chen L, Ewing CM, Eisenberger MA, Carducci MA, Nelson WG, Yegnasubramanian S, Luo J, Wang Y, Xu J, Isaacs WB, Visakorpi T, Bova GS. Nat Med. 2009 Apr 12. [Epub ahead of print]