ESTRO Brachytherapy for Prostate Cancer 2018

The rate of intraprostatic relapses after primary EBRT is still not negligible:

• 20-40% (20-25.000 failure/year)

• 60% - 72% of patients with negative metastatic workup and rising PSA after RT will have positive prostatic biopsies

Zelefsky et al. Int. J. Radiat. Biol. Phys. 1998 Zagars et al. Int. J. Radiat. Biol. Phys. 1995 Pollack et al. Int. J. Radiat. Biol. Phys. 2002

Crook et al. Cancer. 1997 Alongi et al. CROH. 2013