SBRT2015

Dose effect modelling – individual patient data

n=505

n=395

1.0

0.9

0.8

0.7

0.6

0.5

0.4

Local control

0.3

0.2

0.1

0.0

0

20

40

60

80 100 120 140 160 180 200

BED 10

Perscription dose PTV (Gy)

Grills JTO 2010; Ohiri IJROBP 2012

Guckenberger Radiother Oncol 2013

= 3 x 18Gy

Very limited gain in TCP for doses >100Gy BED

Matthias Guckenberger - DEGRO 2015

29.08.2015

25

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