AOAC_SPDS_ERP_-_Set_3
AOAC SPDS ERP - Set 3 Review Form 2
Submission Date
2016-07-28 12:47:46
Name
Martha Jennens
martha.jennens@covance.com
Organization
Covance
Title of Method
Determination of Catechins and Caffeine in Camillia sinensis Raw Materials, Extracts and Dietary Supplements by HPLC-UV: Single Laboratory Validation
AOAC Candidate Method Number (e.g. ALN-01)
TEA-02
Applicable SMPR
2015.014
Summary:
A rapid method to quantify seven catechins and caffeine in green tea raw material and powdered extract and dietary supplements containing green tea extract. The method utilizes RP HPLC with a phenyl column and gradient elution with UV detection and a 13 minute run time.
1. Does the applicability of the method support the applicability of the SMPR? If not, please explain what is missing. 2. Does the analytical technique(s) used in the method meet the SMPR? If not, please specify how it differs from what is stated in the SMPR. 3. Are the definitions specified in the SMPR used and applied appropriately in the method? If no, please indicate how the terms are used. 4. Does the method, as written, contain all appropriate precautions and warnings related to the method's reagents, components, instrumentation, or method steps that may be hazardous? If no, please suggest wording or option(s).
No. The method only applies to seven of eight catechins, one of three methyl xanthines (caffeine) and no theaflavin or theanine is covered.
Yes, but it does not cover all analytes in the SMPR.
Yes
There is no discussion in the method around safety/precautions in use of chemicals, etc.
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