Dose Course 2018_Flipping book

Influence on derived metrics of dose calculation

Hedin, Beck JACMP 2013

• Accuracy of NTCP depends on accuracy of calculated dose distribution • Older dose calculation approaches used for NTCP • PB to AAA: – MLD increase of 5% (lung), 4% (LGB), 4% (Tang Breast) • PB to CC – MLD increase 8%(L), 9% (LGB), 10%(TB) • NTCP reduces as dose sophistication increases – Not for tangential field breast (lateral spread for PB)

Dublin 2018