Haematology 2018

CAR-T Cells in DLBCL

JULIET (CTL019) (n=51)

TRANSCEND (JCAR017) (n=54)

ZUMA-1 (KITE- C19) (n=101)

Best ORR (%)

59

76

82

ORR at 3 months (%)

45

51

-

ORR at 6 months (%)

-

-

36

CR (%)

43

52

49

CR at 3 months (%)

37

39

-

CR at 6 months (%)

-

-

31

Grade 3/4 CRS/neurotoxicity (%)

26/13

2/16

13/28

Tocilizumab/steroids (%)

16/11

11/24

43/27