Haematology 2018

Risks of Second Malignancy following HL combined results from 3 large studies* (n=9618)

Site or Type

Obs

SIR

AER

All SMN

747

3.8

62.2

Solid tumors

519

2.8

37.9

Lung

155

4.3

13.4

GI tract

115

2.4

7.0

Stomach

29

2.8

2.1

Female breast

76

2.7

13.2

Thyroid

14

9.2

1.4

Leukemia

116

22.3

12.5

ANLL

63

94.8

14.9

SIR: Standardized Incidence Ratio; AER: Absolute Excess Risk per 10,000 persons/year *Based on Hancock 1996; Van Leeuwen 2000; Swerdlow 2000