Haematology 2018

Literature on CRC risk after HL or childhood cancer and in A-bomb survivors

• Colorectum: important site of excess cancer in HL survivors • ↑ colon cancer risk after exposure to low RT doses, whereas ↑ rectal cancer risk after higher doses • Excess CRC risk appears 10 years after exposure

Birdwell et al., 1997; Hodgson et al., 2007; Van den Belt- Dusebout et al, 2009; Henderson et al 2012 (CCS); Nottage et al 2012 (CCS);Life Span Studies; Eggermond work in progress