Biophysical Society 59th Annual Meeting Program Guide

1887-P os B oard B24 STRUCTURE AND DYNAMICS OF THE EIIC SUGAR UPTAKE SYSTEM. Zhenning Ren , Ming Zhou 1888-P os B oard B25 PREDICTING THE EFFECTS OF CLINICALLY OBSERVED KINASE MUTATIONS USING MOLECULAR MODELING AND MACHINE LEARNING ALGORITHMS. E. Joseph Jordan , Peter J. Huwe, Yael Mosse, Mark Lemmon, Ravi Radhakrishnan 1889-P os B oard B26 ACTIVATION MECHANISM OF A SIGNALING PROTEIN AT ATOMIC RESOLUTION. Francesco Pontiggia , Dimitar V. Pachov, Michael W. Clarkson, Janice Villali, Michael F. Hagan, Vijay S. Pande, Dorothee Kern 1890-P os B oard B27 CRYSTAL STRUCTURES OF TREHALOSE SYNTHASE FROM DEINOCOCCUS RADIODURANS REVEAL A CLOSED CONFORMATION FOR INTRAMOLECULAR ISOMERIZATION CATALYSIS AND MUTANT INDUCTION OF AN ACTIVE-SITE APERTURE. Sih-Yao Chow , Yung-Lin Wang, Li-Ci Ye, Shwu-Huey Liaw 1891-P os B oard B28 BIOPHYSICAL CHARACTERIZATION OF NATURALLY OCCURRING TITIN-M10 MUTATIONS. Nathan T. Wright , Michael W. Rudloff Protein Dynamics and Allostery II (Boards B29-B49) 1892-P os B oard B29 INVESTIGATING THE MECHANISM OF IRON DEPENDENT REPRESSOR (IDER) ACTIVATION AND DNA BINDING. Soma Ghosh , Nagasuma Chandra, Saraswathi Vishveshwara 1893-P os B oard B30 DYNAMIC CHARACTERISTICS OF ALLOSTERIC PATHWAYS IN SCFV ANTIBODY FRAGMENTS. Amit Srivastava , Malgorzata B. Tracka, Shahid Uddin, Jose Casas-Finet, Dennis R. Livesay, Donald J. Jacobs 1894-P os B oard B31 FUNCTIONALLY IMPORTANT RESIDUES FROM MODE COUPLING DURING SHORT-TIME PROTEIN DYNAMICS. Onur Varol, Deniz Yuret, Burak Erman, Alkan Kabakcioglu 1895-P os B oard B32 HIGH-SPEED AFM OBSERVATION OF ANTIBODY IGG CHARACTERISTIC OF SWINGING ARMS. Norito Kotani , Tomohiro Hirano, Takashi Morii, Takao Okada 1896-P os B oard B33 VISUALIZING GLOBAL PROPERTIES OF A MOLECULAR DYNAMICS TRAJECTORY. Hao Zhou , Shangyang Li, Makowski Lee 1897-P os B oard B34 COMPUTATIONAL MODELING OF THE FC α RI RECEPTOR BINDING IN THE FC α DOMAIN OF THE HUMAN ANTIBODY IGA: CORSE-GRAINED MOLECULAR DYNAMICS (MD) METHODS. Manori Jayasinghe , Monica T. Posgai, Sam Tonddast- Navaei, George M. Ibrahim, George Stan, Andrew B. Herr

1898-P os B oard B35 COMPUTER-AIDED DRUG DISCOVERY APPROACH FINDS CALCIUM SENSITIZER OF CARDIAC TROPONIN. Steffen Lindert , Monica X. Li, Brian Sykes, J. Andrew McCammon 1899-P os B oard B36 A COARSE-GRAINED LANGEVIN EQUATION FOR PROTEIN DYNAMICS: GLOBAL ANISOTROPY AND A MODE APPROACH TO LOCAL COMPLEXITY. Jeremy T. Copperman , Marina G. Guenza 1900-P os B oard B37 LOOKING AT ESTROGEN RECEPTOR FROM SMALL ANGLES. Sichun Yang , Wei Huang, Krishna M. Ravikumar 1901-P os B oard B38 education travel awardee STUDY OF PROTON TRANSFER IN ESCHERICHIA COLI PHOTOLYASE. Meng Zhang , Zheyun Liu, Jiang Li, Lijuan Wang, Dongping Zhong 1902-P os B oard B39 ABROGATING RAS ABNORMAL FUNCTION BY TARGETING MEMBRANE BOUND RAS MONOMERS AND OLIGOMERS. Priyanka Prakash Srivastava , Alemayehu A. Gorfe 1903-P os B oard B40 IDENTIFYING TRANSIENT BINDING POCKETS IN PROTEIN DYNAMICS FOR ALLOSTERIC DRUG DESIGN. Supriyo Bhattacharya , Vinod Kasam, Hubert Li, Nagarajan Vaidehi 1904-P os B oard B41 LEARNING ABOUT TRANSITIONS: ADAPTIVE CONTROL IN THE MOLECULAR MARSHAL (M2) FRAMEWORK. Thomas B. Woolf , Sarana Y. Nutanong, Yanif Ahmad, Raman Arora 1905-P os B oard B42 CHARACTERIZING DYNAMICS OF ANION/PI INTERACTIONS THROUGH MOLECULAR DYNAMICS SIMULATIONS. Karan Kapoor , Michael Duff, Robert Hinde, Jerome Baudry, Elizabeth Howell 1906-P os B oard B43 SIMULTANEOUS IDENTIFICATION, VISUALIZATION, AND COMPARISON OF COMPLEX EVENTS IN MOLECULAR DYNAMICS SIMULATIONS. Michael V. LeVine , George Khelashvili, Harel Weinstein 1907-P os B oard B44 UNRAVELING THE DYNAMICS OF THE EF1 HAND UPON CA 2+ BINDING IN NEUROCALCIN DELTA. Yang Yang , Anuradha Krishnan, Jeffrey Viviano, Venkat Venkataraman 1908-P os B oard B45 MECHANICAL PROPERTIES OF DNA BINDING PROTEINS: TALES IN SILICO. Yuichi Togashi , Naoya Tochio 1909-P os B oard B46 WATCHING CONFORMATIONAL CHANGES IN PROTEINS BY MOLECULAR DYNAMICS SIMULATIONS. Kresten Lindorff-Larsen 1910-P os B oard B47 A HINGE MIGRATION MECHANISM UNLOCKS THE EVOLUTION OF GREEN-TO-RED PHOTOCONVERSION IN GFP-LIKE PROTEINS. Rebekka M. Wachter , Hanseong Kim, Taisong Zou, S. Banu Ozkan

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Biophysical Society 59 th Annual Meeting, Baltimore, Maryland