Biophysical Society 59th Annual Meeting Program Guide

1945-P os

B oard B82

Intrinsically Disordered Proteins (IDP) and Aggregates III (Boards B71-B94) 1934-P os B oard B71 SECONDARY METAL BINDING TO AMYLOID-BETA MONOMER IS INSIGNIFICANT UNDER SYNAPTIC CONDITIONS. Thomas Branch, Mauricio Barahona, Liming Ying 1935-P os B oard B72 GAS-PHASE CONFORMATIONS OF A HUNTINGTIN N-TERMINAL PEPTIDE REVEAL CONDENSED-PHASE HETEROGENEITY WITH AND WITHOUT THE PRESENCE OF A PPII HELIX. James R. Arndt , Samaneh G. Kondalaji, Olivia Sarver, Megan M. Maurer, Arlo Parker, Justin Legleiter, Stephen J. Valentine 1936-P os B oard B73 HUNTINGTIN N-TERMINAL FRAGMENT FIBRILS HAVE A RIGID AMYLOID CORE FLANKED BY NON-AMYLOID DOMAINS WITH INCREASED DYNAMICS. Cody L. Hoop, Hsiang- Kai Lin, Karunakar Kar, Ronald Wetzel, Patrick C A van der Wel 1937-P os B oard B74 INITIATING POLYGLUTAMINE AGGREGATION --- COMPUTATIONAL CLARIFICATION OF THE STRUCTURAL DETAILS. Markus S. Miettinen , Luca Monticelli, Praveen Nedumpully- Govindan, Volker Knecht, Zoya Ignatova 1938-P os B oard B75 international travel awardee THE ROLE OF STRUCTURAL DYNAMICS IN DETERMINING THE PRION STRAIN DIVERSITY. Dominic Narang , Anup K. Srivastava, Samrat Mukhopadhyay 1939-P os B oard B76 education travel awardee AMYLOIDOGENICITY OF IMMUNOGLOBULIN LIGHT CHAINS. Kathrin Andrich , Ute Hegenbart, Stefan Schönland, Erich Wanker, Jan Bieschke 1940-P os B oard B77 PREDICTION OF THE EFFECTS OF THE VAL66MET POLYMORPHISM AND ADJACENT STRUCTURED DOMAINS ON THE CONFORMATIONAL ENSEMBLE OF AN INTRINSICALLY DISORDERED PROTEIN, BRAIN-DERIVED NEUROTROPHIC FACTOR. Ruchi Lohia , Reza Salari, Grace B oard B78 STRUCTURAL STABILITY OF DIABETES-RELATED AMYLIN PROTOFILAMENTS: APPLICATIONS TO FIBRIL DESIGN. Ye Yuan , Bartlomiej Tywoniuk, Nicolae-Viorel Buchete 1942-P os B oard B79 EXPLOSIVE FIBRILLATION KINETICS OF TWO-CHAIN INSULIN FRAGMENT RELEASED UPON PARTIAL DIGESTION WITH PEPSIN. Wojciech Dzwolak , Marcin Piejko, Robert Dec, Viktoria Babenko, Agnieszka Hoang, Monika Szewczyk, Pawel Mak 1943-P os B oard B80 ELUCIDATING THE ROLE OF OLIGOMERS IN INSULIN AGGREGATION USING BIOPHYSICAL METHODS. Matthew T. Mawhinney , Brigita Urbanc 1944-P os B oard B81 DMSO INDUCED BREAKING UP OF INSULIN FIBRILS MONITORED BY VIBRATIONAL CIRCULAR DICHROISM. Ge Zhang , Viktoria Babenko, Wojciech Dzwolak, Timothy A. Keiderling Brannigan 1941-P os

education travel awardee THE INTRINSICALLY DISORDERED TERMINI OF ZDHHC S-PALMITOYLTRANSFERASES FACILITATE MULTIPLE REGULATORY FUNCTIONS. Krishna D. Reddy , Jeremy D. Baker, Bin Xue, Robert J. Deschenes, Vladimir N. Uversky 1946-P os B oard B83 PROTEIN DISORDER IN DYNEIN REGULATION BY DYNACTIN AND NUDE. Jing Jie , Elisar Barbar 1947-P os B oard B84 A FUZZY DNA BINDING REGION IN MBD2 RECRUITS THE HISTONE DEACETYLASE CORE COMPLEX OF NURD AND MODIFIES KINETICS OF DNA BINDING. David C. Williams , Megha Desai, Gordon D. Ginder 1948-P os B oard B85 C/EBP β : CASE STUDY FOR THE IMPORTANCE OF INTRINSIC DISORDER FOR PROTEIN FUNCTION. Maria Miller 1949-P os B oard B86 STRUCTURAL AND DYNAMIC ANALYSIS ON DISORDERED H4 HISTONE TAIL BY MODIFIED AWSEM-MD. Hao Wu , Garegin Papoian 1950-P os B oard B87 THE ACETYLATION LANDSCAPE OF THE H4 HISTONE TAIL. David Winogradoff , Ignacia Echeverria, Garegin Papoian 1951-P os B oard B88 COMPARING SOLUTION STRUCTURES OF AMYLIN AND CGRP BY NANOSECOND LASER-PUMP SPECTROSCOPY AND ATOMISTIC SIMULATIONS. Sara M. Sizemore, Gül H. Zerze, Stephanie M. Cope, Jeetain Mittal, Sara M. Vaiana 1952-P os B oard B89 PRIMARY SEQUENCE CONTROLS THE SPECIFICITY AND AFFINITY OF A SMALL MOLECULE BINDING TO THE INTRINSICALLY DISORDERED PROTEIN C-MYC. Lisette M. Fred , Kaitlyn P. Gerhart, Bethany L. Zablotsky, Scott A. Barnett, Steven J. Metallo 1953-P os B oard B90 INTERACTION OF THE INTRINSICALLY DISORDERED C-MYC ONCOPROTEIN WITH RACEMIC AND ENANTIOPURE SMALL MOLECULES. Kaitlyn P. Gerhart , Steven J. Metallo 1954-P os B oard B91 THE INTRINSICALLY DISORDERED C-TERMINAL TAILS OF E.COLI SINGLE-STRANDED DNA BINDING PROTEIN REGULATE COOPERATIVE BINDING TO SINGLE-STRANDED DNA. Alexander G. Kozlov , Elizabeth Weiland, Anuradha Mittal, Vince Waldman, Rohit V. Pappu, Lohman M. Timothy 1955-P os B oard B92 ASSESSING BINDING PERTURBATION DUE TO ARTIFICIAL VIBRATIONAL PROBE GROUPS IN THE NUCLEOPROTEIN- PHOSPHOPROTEIN COMPLEX OF THE NIPAH VIRUS. Rebecca B. Wai , Shana R. Burstein, Sara K. Hess, Jenny Erales, Sonia Longhi, Casey H. Londergan 1956-P os B oard B93 CLAWS, DISORDER, AND CONFORMATIONAL DYNAMICS OF THE C TERMINAL REGION OF HUMAN DESMOPLAKIN. Charles E. McAnany , Cameron Mura

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Biophysical Society 59 th Annual Meeting, Baltimore, Maryland