Biophysical Society 59th Annual Meeting Program Guide

2196-P os B oard B333 MECHANISMS OF TREK-2 POTASSIUM CHANNEL GATING. Conor McClenaghan , Elizabeth Carpenter, Tucker J. Stephen 2197-P os B oard B334 THE MOLECULAR BASIS FOR HEME MODULATION OF KATP CHANNELS. Mark Burton , Sofia Kapetanaki, Noel Davies, John Mitcheson, Ralf Schmid, Peter Moody, Emma Raven, Nina Storey 2198-P os B oard B335 NMR STRUCTURAL STUDIES OF THE BINDING OF ACTIVATING MAMBA TOXIN TX7335 ON THE POTASSIUM CHANNEL KCSA. Jing Zhu , Ulfat Shahzad, Sebastien F. Poget 2199-P os B oard B336 MECHANISM OF INHIBITION OF THE GLUA1 AMPA RECEPTOR CHANNEL OPENING BY 2,3-BENZODIAZEPINE COMPOUNDS. AndrewWu 2200-P os B oard B337 SIMULTANEOUS MEASUREMENTS OF INTRACELLULAR [CA 2+ ]I AND [CAMP]I IN INTACT ISLETS TO STUDY THE MECHANISM UNDERLYING DOPAMINERGIC INHIBITION OF INSULIN SECRETION. Alessandro Ustione , David W. Piston 2201-P os B oard B338 DETERMINING THE DOPAMINERGIC FEEDBACK PATHWAY IN PANCREATIC β -CELLS WITH FLUORESCENCE FLUCTUATION SPECTROSCOPY. Brittany Caldwell , Alessandro Ustione, David Piston Other Channels (Boards B339-B366) 2202-P os B oard B339 STATISTICAL ANALYSIS OF MULTICHANNEL SIGNALS. Rishabh Kumar, Prashant Srinivasa, Horia I. Petrache 2203-P os B oard B340 NOVEL STEP DETECTION ALGORITHMS FOR PHOTOBLEACHING ANALYSIS OF PROTEIN COMPLEXES WITH MANY SUBUNITS. Nathan C. Deffenbaugh , Yalei Chen, Charles T. Anderson, William O. Hancock 2204-P os B oard B341 SINGLE-FILE WATER PERMEATION THROUGH AQUAPORIN CHANNELS. Peter H. Nelson 2205-P os B oard B342 MAKING AN AQUAPORIN WATER-TIGHT: STRUCTURAL BASIS OF SELECTIVITY IN PLANT NODULIN 26 INTRINSIC PROTEINS. Zachary G. Beamer , Tian Li, Jerome Baudry, Daniel M. Roberts 2206-P os B oard B343 MECHANISM OF PROTON TRANSPORT OF THE M2 PROTON CHANNEL STUDIED BY CONSTANT PH MOLECULAR DYNAMICS. Wei Chen , Jana K. Shen 2207-P os B oard B344 PROTON PERMEATION IN CI-HV1 VOLTAGE-GATED PROTON CHANNELS OCCURS THROUGH A PROTON WIRE INVOLVING RESIDUES D160 AND D222 AND IT IS MODULATED BY N264. Amaury Pupo , David Baez-Nieto, Ester Otarola, Osvaldo Yañez, Ariela Vergara-Jaque, Wendy Gonzalez, Karen Castillo, Gustavo Contreras, H. Peter Larsson, Ramón Latorre, Carlos Gonzalez

2208-P os B oard B345 FREE ENERGY SIMULATIONS OF ION TRANSLOCATION THROUGH VOLTAGE-GATED PROTON CHANNEL HV1. Kethika Kulleperuma , Susan M. E. Smith, Thomas E. DeCoursey, Regis Pomes 2209-P os B oard B346 INVESTIGATING THE POTENTIATION EFFECT OF 2-APB ON CRAC CHANNELS. Xiaolan Xu , Sher Ali Syed, Tao Xu 2210-P os B oard B347 SLO2.X POTASSIUM CHANNELS ARE INVOLVED IN THE REGULATION OF HEART MITOCHONDRIAL FUNCTION. Charles Owen Smith 2211-P os B oard B348 HUMAN ERYTHROCYTE MECHANO-ACTIVATED K + CHANNEL A, A KINETIC STUDY OF INTRABURST ACTIVITY: EFFECT OF CHLORPROMAZINE. Alejandro Mata, Jesus G. Romero 2212-P os B oard B349 MECHANISMS UNDERLYING THE LOSS-OF-FUNCTIONAL KIR6.1 KATP CHANNEL MUTATIONS IN SUDDEN INFANT DEATH SYNDROME. Bi-Hua Tan , Blaise Z. Peterson, Ryan Li, Tianyu Sun, Sinisa Dovat, Michael J. Ackerman, Chunhua Song 2213-P os B oard B350 STUDYING CLUSTERING OF KCSA CHANNELS USING SINGLE- CHANNEL VOLTAGE-CLAMP FLUORESCENCE IMAGING. Hugo McGuire , Rikard Blunck 2214-P os B oard B351 CRYSTAL STRUCTURE OF FLUC, A MICROBIAL FLUORIDE CHANNEL. Randy Stockbridge , Ludmila Kolmakova-Partensky, Akiko Koide, Shohei Koide, Simon Newstead, Christopher Miller 2215-P os B oard B352 TWO-SIDED SIMULTANEOUS BLOCK OF A F- CHANNEL (FLUC). Daniel L. Turman , Randy Stockbridge, Christopher Miller 2216-P os B oard B353 REGULATION OF CLC-3 CL-/H + TRANSPORT AND “GATING” TRANSIENTS BY CHLORIDE PATHWAY RESIDUES AND EXTERNAL PROTONS. Jeffrey Rohrbough , Fred S. Lamb, Hong- Ngan Nguyen 2217-P os B oard B354 ENERGETICS AND MECHANISM OF PERMEATION ACROSS FNT CHANNELS. Kalina Atkovska , Jochen Hub 2218-P os B oard B355 international travel awardee EXTRACELLULAR CHLORIDE REGULATES TMEM16A GATING. Juan A. Contreras-Vite, Silvia Cruz-Rangel , Patricia Pérez- Cornejo, H. Criss Hartzell, Jorge Arreola 2219-P os B oard B356 ACTIVATION OF ATP SECRETION VIA VOLUME-REGULATED ANION CHANNELS BY SPHINGOSINE-1-PHOSPHATE IN RAW MACROPHAGES. Philipp Burow, Manuela Klapperstück, Fritz Markwardt 2220-P os B oard B357 POSITIONING OF THE FIRST EXTRACELLULAR LOOP OF CFTR HAS SIGNIFICANT EFFECTS ON CFTR GATING. Daniel T. Infield , Guiying Cui, Christopher Kuang, Nael A. McCarty

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Biophysical Society 59 th Annual Meeting, Baltimore, Maryland