Biophysical Society 59th Annual Meeting Program Guide

2864-P os B oard B294 STIM1 AND STIM2 PROTEINS REGULATION OF

2875-P os B oard B305 CALCIUM SIGNALING AMONG RYR2S WITHIN A CALCIUM RELEASE UNIT DURING A CALCIUM SPARK. Didier X.P. Brochet , Gang Wang, W. Jonathan Lederer, Heping Cheng 2876-P os B oard B306 BIOORTHOGONAL CALCIUM MODULATION BY DIRECT INTRACELLULAR ACCESS USING NANOSTRAWS. Alexander Xu , Amin Aalipour, Sally Kim, Nicholas Melosh 2877-P os B oard B307 EFFECTS OF ARRHYTHMOGENIC MUTATIONS ON CA 2+ - INDUCED CA 2+ RELEASE ACTIVITIES OF TYPE 2 RYANODINE RECEPTORS. Nagomi Kurebayashi , Takashi Murayama, Junji Suzuki, Kazunori Kanemaru, Masamitsu Iino, Takashi Sakurai 2878-P os B oard B308 FILLING THE GAP BETWEEN CALCIUM SPARKS AND WAVES: AUTOMATIC DETECTION AND CLASSIFICATION OF LOCAL CALCIUM RELEASES IN CARDIAC PACEMAKER CELLS. Alexander V. Maltsev , Michael D. Stern 2880-P os B oard B310 BASAL ACTIVITY OF EPIDERMAL GROWTH FACTOR RECEPTOR (EGFR) AND PHOSPHOLIPASE C (PLC) ARE REQUIRED TO SUSTAIN SPONTANEOUS BEATING OF CARDIAC PACEMAKER CELLS. Tatiana M. Vinogradova , Kirill V. Tarasov, Edward G. Lakatta 2881-P os B oard B311 A NEW SIMPLIFIED 3D MODEL OF CARDIAC PACEMAKER CELL BASED ON SUPERRESOLUTION STRUCTURED ILLUMINATION MICROSCOPY (SIM). Victor A. Maltsev , Oliver Monfredi, Hari Shroff, Andrew G. York, Anna V. Maltsev, Edward G. Lakatta, Michael D. Stern 2882-P os B oard B312 GLYCOSIDE-INDUCED COLLAPSE OF THE SODIUM AND CALCIUM GRADIENTS LEADS TO A BIPHASIC EFFECT ON CARDIAC CELL PACEMAKER FUNCTION. Rostislav Bychkov , Syevda Sirenko, Yael Yaniv, Victor A. Maltsev, Edward G. Lakatta 2883-P os B oard B313 AUTONOMIC STIMULATION MODULATES ACTION POTENTIAL FIRING RATE IN CARDIAC PACEMAKER CELLS VIA SYNCHRONIZATION OF LOCAL CALCIUM PUMPING AND RELEASE. Oliver J. Monfredi , Edward G. Lakatta, Victor A. Maltsev 2884-P os B oard B314 EXCITATION-METABOLISM COUPLING IN MOUSE HEART. Andrew P. Wescott , W. J. Lederer, George S. B. Williams 2885-P os B oard B315 SIMILARITIES AND DIFFERENCES IN GATING OF THE TWO- PORE CHANNELS TPC1 AND TPC2. Archana Jha , Malini Ahuja, Shmuel Muallem 2886-P os B oard B316 MITOCHONDRIAL CALCIUM AND BIOENERGETICS CONTROLLED BY TIGHT COORDINATION OF MCU AND NCLX. Ming-Feng Tsai , Chuck Phillips, Christopher Miller DHBP BLOCK OF RYANODINE RECEPTOR CHANNELS. Yuanzhao Lv , Julio A. Copello 2879-P os B oard B309

ENDOGENOUS STORE-OPERATED CALCIUM CHANNELS IN HEK293 CELLS. Alexey Shalygin , Olga Zimina, Vera Kamaletdinova, Anton Skopin, Lyuba Glushankova, Galina N. Mozhayeva, Elena Kaznacheyeva 2865-P os B oard B295 STIM1-STIM2 INTERACTIONS MODULATE STORE-OPERATED CALCIUM ENTRY. Krishna Subedi , Hwei Ling Ong, Indu Ambudkar 2866-P os B oard B296 REMODELING OF THE CYTOSKELETON AND REGULATION OF STORE-OPERATED CALCIUM ENTRY. Lorena de Souza , Timothy Lockwich, Hwei Ling Ong, Kwong Tai Cheng, Indu S. B oard B297 A NOVEL STIM2 SPLICE VARIANT FUNCTIONS AS A BREAK FOR STIM MEDIATED ACTIVATION OF ORAI CALCIUM CHANNELS. Anna-Maria Miederer , Dalia Alansary, Gertrud Schwaer, Martin Jung, Barbara A. Niemeyer 2868-P os B oard B298 ROLES OF THE ORAI1 C-TERMINUS AND N-TERMINUS IN 2-APB-INDUCED STIM1 COUPLING. Yandong Zhou , Youjun Wang, Xizhuo Wang, Natalia A. Loktionova, Xianming Wang, Donald L. Gill 2869-P os B oard B299 international travel awardee MENTHOL-INDUCED CHANGES IN MESENCHYMAL STEM CELL DIFFERENTIATION. Juan C. Henao, Adriana Grismaldo, Yolima P. Torres Intracellular Calcium Channels and Calcium Sparks and Waves II (Boards B300-B316) 2870-P os B oard B300 MICU1 AND MICU2 OPERATE TOGETHER TO REGULATE THE UNIPORTER. Kimberli J. Kamer , Vamsi K. Mootha 2871-P os B oard B301 ACTIVATION OF MITOCHONDRIAL SK CHANNELS IN CARDIOMYOCYTES DERIVED FROM HYPERTROPHIC HEARTS ATTENUATES CCA 2+ -DEPENDENT ARRHYTHMIA BY REDUCING MITOCHONDRIAL ROS PRODUCTION THEREBY STABILIZING RYRS. TaeYun Kim, Weiyan Li, Karim Roder, Radmila Terentyeva, Gideon Koren, Bum-Rak Choi, Dmitry Terentyev 2872-P os B oard B302 ALTERED RYANODINE RECEPTOR FUNCTION IN ISCHEMIC HEART DISEASE: IS THERE A ROLE FOR MITOCHONDRIA? Demetrio J. Santiago , Eef Dries, Ilse Lenaerts, Karin R. Sipido 2873-P os B oard B303 STATIN INDUCED MYOPATHY: A ROLE FOR MITOCHONDRIAL CA 2+ AND NO IN ENHANCED SARCOPLASMIC RETICULUM CA 2+ LEAK. Sabine Lotteau , David MacDougall, Derek Steele, Sarah Calaghan 2874-P os B oard B304 RIESKE IRON-SULFUR PROTEIN-DEPENDENT MITOCHONDRIAL ROS-MEDIATED DISSOCIATION OF FKBP12.6/RYR2 COMPLEX PLAYS AN ESSENTIAL ROLE IN PULMONARY HYPERTENSION. Yong-Xiao Wang , Yun-Min Zheng Ambudkar 2867-P os

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Biophysical Society 59 th Annual Meeting, Baltimore, Maryland