Biophysical Society 59th Annual Meeting Program Guide

3073-P os B oard B503 CARDIOPROTECTIVE ROLES OF NEURONAL CA 2+ SENSOR-1 DURING STRESS. Tomoe Y. Nakamura-Nishitani , Shu Nakao, Shigeo Wakabayashi 3074-P os B oard B504 INITIATION OF ELECTRON TRANSPORT ACTIVITY AND A DECREASE OF OXIDATIVE STRESS OCCUR SIMULTANEOUSLY DURING EMBRYONIC HEART DEVELOPMENT. Gisela Beutner, George A. Porter, Jr. 3075-P os B oard B505 cpow travel awardee THE STOICHIOMETRY BETWEEN MICU1 AND MCU DETERMINES THE DIFFERENT MITOCHONDRIAL CA 2+ UPTAKE PHENOTYPES IN HEART AND LIVER. Melanie Paillard , György Csordás, Tünde Golenár, Cynthia Moffat, Erin Seifert, György B oard B506 ER CALCIUM RELEASE IS TUNED BY MITOCHONDRIAL REDOX NANODOMAINS. David M. Booth , Balázs Enyedi, Miklós Geiszt, Péter Várnai, György Hajnóczky 3077-P os B oard B507 REACTIVE OXYGEN SPECIES (ROS) SUPPRESS MITOCHONDRIAL MOTILITY. Valentina Debattisti , Masao Saotome, Sudipto Das, Gyorgy Hajnoczky 3078-P os B oard B508 MIRO1 IS DISPENSABLE FOR CALCIUM-MEDIATED INHIBITION OF MITOCHONDRIAL MOVEMENT. David B. Weaver , Agnieszka Lewandowska, Tammy T. Nguyen, Valentina Debattisti, Janet M. Shaw, Gyorgy Hajnoczky 3079-P os B oard B509 MITOCHONDRIAL FUSION DYNAMICS IN THE HEART. Veronica Eisner , Ryan Cupo, Erhe Gao, György Csordás, Lan Cheng, Jessica Ibetti, J. Kurt Chuprun, Walter J. Koch, György Hajnóczky 3080-P os B oard B510 MECHANISTIC CHARACTERIZATION OF THE THIOREDOXIN SYSTEM IN THE REMOVAL OF HYDROGEN PEROXIDE. Venkat R. Pannala , Ranjan K. Dash 3081-P os B oard B511 HIGHER MITOCHONDRIAL MEMBRANE POTENTIAL INDUCES ROS PRODUCTION IN THE FAMILIAR FORM OF FRONTOTEMPORAL DEMENTIA WITH MAPT MUTATIONS. Noemi Esteras Gallego , Selina Wray, Elisavet Preza, Andrey Y. Abramov 3082-P os B oard B512 international travel awardee THE OVEREXPRESSION OF SUPEROXIDE DISMUTASE 1 RESTORES GROWTH DEFECT IN A PORIN1-LESS YEAST STRAIN AND IMPROVES MITOCHONDRIAL METABOLISM. Andrea Magrì , Simona Reina, Flora M. Tomasello, Maria C. Di Rosa, Angela Messina, Vito De Pinto 3083-P os B oard B513 THE ROLE OF COMPLEX I IN MITOCHONDRIAL REACTIVE OXYGEN SPECIES FORMATION IN COCHLEAR SENSORY AND SUPPORTING CELLS DURING OTOTOXIC AMINOGLYCOSIDE EXPOSURE. Danielle Desa , Michael G. Nichols, Heather Jensen Smith 3084-P os B oard B514 MITOCHONDRIAL IRON AND SPHINGOSINE SYNERGIZE INITIATION OF HEPATOCYTE DEATH BY AUGMENTING OXIDATIVE STRESS. Sergei A. Novgorodov , Tatyana I. Gudz, Andaleb Kholmukhamedov, Raymond Deepe, John J. Lemasters Hajnóczky 3076-P os

Cellular Signaling and Metabolic Networks (Boards B515-B530) B oard B515 GUARDIAN FUNCTION OF MITSUGUMIN 53 IN CELL MEMBRANE REPAIR AND METABOLIC SYNDROME. Hanley Ma , Jason Liu, Zehua Bian, Yuqi Cui, Xinyu Zhou, Xuefeng Zhou, Bo Zhang, Timothy M. Adesanya, Ki Ho Park, Hua Zhu 3086-P os B oard B516 NON-INVASIVE INTEROGATION OF SIGNALING ACTIVATED GENE REGULATION. Gregor Neuert 3087-P os B oard B517 MONTE CARLO SIMULATION OF WNT PROPAGATION BY A NOVEL TRANSPORT MECHANISM COMPLEMENTING A JOINT EXPERIMENTAL STUDY. Claude Sinner , Eliana Stanganello, Anja I.H. Hagemann, Benjamin Mattes, Dana Meyen, Sabrina Weber, Erez Raz, Steffen Scholpp, Alexander Schug 3088-P os B oard B518 A GENETICALLY-ENCODED FRET SENSOR BASED ON AMP- ACTIVATED PROTEIN KINASE REPORTS ALLOSTERIC KINASE ACTIVATION. Uwe Schlattner , Martin Pelosse, Imre Berger 3089-P os B oard B519 INTEGRATED OMIC ANALYSIS OF A GUINEA PIG MODEL OF HEART FAILURE AND SUDDEN CARDIAC DEATH. D. Brian Foster , Ting Liu, Robert N. O’Meallly, C. Conover Talbot Jr., Robert N. Cole, Brian O’Rourke 3090-P os B oard B520 CELLULAR SIGNALING NETWORKS FUNCTION AS GENERALIZED WIENER-KOLMOGOROV FILTERS TO SUPPRESS NOISE. Michael Hinczewski , Devarajan Thirumalai 3091-P os B oard B521 TO GROW IS NOT ENOUGH: THE IMPACT OF CELL RESPONSE TIME ON FITNESS. Nash Rochman , Fangwei Si, Sean Sun 3092-P os B oard B522 BCL-2 OVEREXPRESSION STIMULATES GLYCOLYSIS AND LACTIC FERMENTATION IN A BAX-DEPENDENT FASHION. Bushra Mahmood, Jessica Wilson, Miriam Ahmad, Patricia Olino, Justin King, Laurent Dejean 3093-P os B oard B523 HUMAN ADIPOSE CELL RESPONSE TO INSULIN: ANALYSIS OF CELLULAR SWITCH-LIKE TRANSFORMATIONS AND DISTRIBUTIONS. Vladimir A. Lizunov, Paul S. Blank , Karin G. Stenkula, Monica Skarulis, Samuel Cushman, Joshua Zimmerberg 3094-P os B oard B524 ACCELERATING SYSTEMS BIOLOGY COMPUTATION: ENHANCED SAMPLING OF SPATIALLY REALISTIC STOCHASTIC MODELS USING THE WEIGHTED ENSEMBLE APPROACH. Rory Donovan 3095-P os B oard B525 ACCUMULATIONS AND ENERGY RECYCLING PATHWAY IN P. FALCIPARUM GAMETOCYTE-INFECTED HUMAN ERYTHROCYTES. Fuyuki Tokumasu , Takeshi Q. Tanaka, Suzumi Tokuoka, Daichi Nakatani, Shin-ichiro Kawazu, Kiyoshi Kita 3096-P os B oard B526 PHOTO-REGULATION OF THE INTERACTION BETWEEN RAS AND RALGDS USING GTP ANALOGUES COMPOSED OF PHOTOCHROMIC MOLECULES. Kaori Masuhara, Seigo Iwata, Nobuhisa Umeki, Shinsaku Maruta 3085-P os

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Biophysical Society 59 th Annual Meeting, Baltimore, Maryland