Biophysical Society 59th Annual Meeting Program Guide

178-P lat 4:15 pm HIGH TEMPERATURE SENSITIVITY IS INTRINSIC TO VOLTAGE-GATED POTASSIUM CHANNELS. Fan Yang , Jie Zheng 179-P lat 4:30 pm PERMEATION AND DYNAMICS OF AN OPEN-ACTIVATED TRPV1 CHANNEL. Carmen Domene , Leonardo Darre, Simone Furini 180-P lat 4:45 pm THE L596-W733 BOND BETWEEN S4-S5 LINKER AND TRP DOMAIN MAINTAINS BASAL ACTIVITY AND ENABLES INACTIVATION OF TRPV4. Jinfeng Teng , Stephen Loukin, Andriy Anishkin, Ching Kung 181-P lat 5:00 pm COMPARATIVE SEQUENCE ANALYSIS SUGGESTS A UNIFIED GATING MECHANISM FOR TRP CHANNELS. Vincenzo Carnevale , Eugene Palovcak, Lucie Delemotte, Michael Klein 182-P lat 5:15 pm EFFECTS OF INACTIVATION OF TRPM7 KINASE ACTIVITY ON ITS CHANNEL ACTIVITY IN MICE. Taku Kaitsuka, Chiaki Katagiri, Pavani Beesetty, Kenji Nakamura, Siham Hourani, Kazuhito Tomizawa, J. Ashot Kozak , Masayuki Matsushita 183-P lat 5:30 pm TEMPERATURE AND VOLTAGE COUPLING TO TRPM8 CHANNEL OPENING. Natalia Raddatz, Juan P. Castillo , Carlos Gonzalez, Osvaldo Alvarez, Ramon Latorre 184-P lat 5:45 pm TRPM8 IS AN IONOTROPIC TESTOSTERONE RECEPTOR. Swapna Asuthkar, Lusine Demirkhanyan, Xiaohui Sun, Pia Elustondo, Vivek Krishnan, Padmamalini Baskaran, Kiran Kumar Velpula, Baskaran Thyagarajan, Evgeny Pavlov, Eleonora Zakharian Co-Chairs Blake Mertz, West Virginia University Svetla Stoilova-McPhie, University of Texas Medical Branch at Galveston 185-P lat 4:00 pm EXPERIMENTAL AND COMPUTATIONAL STUDIES OF PULMONARY SURFACTANT PROTEIN SP-B INTERACTING WITH LIPID BILAYERS. Mohammad Hassan Khatami , Ivan Saika-Voivod, Valerie Booth 186-P lat 4:15 pm CREATION OF WATER-SOLUBLE INTEGRAL MEMBRANE PROTEINS USING AN ENGINEERED AMPHIPATHIC PROTEIN “SHIELD”. Dario Mizrachi 187-P lat 4:30 pm VALIDATING THE RETINAL FLIP OF RHODOPSIN USING MOLECULAR DYNAMICS. Jun Feng, Blake Mertz 188-P lat 4:45 pm HIV GP41-ANTIBODY INTERACTION AT THE VIRAL MEMBRANE INTERFACE DEFINED BY EPR SPECTROSCOPY. Likai Song , Zhen-Yu J. Sun, Mikyung Kim, Pavanjeet Kaur, Gerhard Wagner, Ellis L. Reinherz 4:00 pm –6:00 pm , R oom 309/310 Platform Protein Lipid Interactions I

168-Symp 5:30 pm AN INTEGRATIVE APPROACH TO THIN FILAMENT CARDIO- MYOPATHIES: FROM MOLECULAR AND COMPUTATIONAL BIOPHYSICS TO MICE. Jil Tardiff 4:00 pm –6:00 pm , B allroom IV Platform Optical Microscopy and Super-Resolution Imaging I Co-Chairs Keith Lidke, University of New Mexico Christopher Kelly, Wayne State University 169-Plat 4:00 pm REFLECTED BEAM LIGHT-SHEET MICROSCOPY FOR WHOLE- CELL 3D SUPER-RESOLUTION IMAGING. Marjolein BM Meddens , Sheng Liu, Conrad D. James, Keith A. Lidke 170-P lat 4:15 pm PROBING THE TRANSCRIPTION CYCLE IN REAL-TIME WITH 3D SUPERRESOLUTION INTERFEROMETRY. Guanshi Wang , Jesse Hauver, Zachary Thomas, Seth A. Darst, Alexandros Pertsinidis 171-P lat 4:30 pm minority affairs travel awardee RESOLVING NANOSCALE CURVATURE ON LIPID BILAYERS WITH POLARIZED LOCALIZATION MICROSCOPY. Abir Maarouf , Rebecca Lynn Meerschaert, Christopher V. Kelly 172-P lat 4:45 pm SPATIAL AND FUNCTIONAL ORGANIZATION OF BACTERIAL SUBCELLULAR STRUCTURES IN SUPERRESOLUTION. Jie Xiao , Carla Coltharp, Xiaoli Weng, Jackson Buss, Xinxing Yang, Arvin Lagda 173-P lat 5:00 pm DISEASE PHENOTYPING WITH SUB-RESOLUTION PRECISION BY SINGLE MOLECULE TRACKING IN LIVE ANIMALS. Hong Zhan, Ramunas Stanciauskas, Christian Stigloher, Kevin Dizon, Maelle Jospin, Jean-Louis Bessereau, Fabien Pinaud 174-P lat 5:15 pm SUPER RESOLUTION FLUORESCENCE MICROSCOPY BY CATHODOLUMINESCENCE-ACTIVATED EXCITATION. Connor G. Bischak , Craig L. Hetherington, Jake T. Precht, Claire E. Stachelrodt, Zhe Wang, Darrell G. Schlom, Naomi S. Ginsberg 175-P lat 5:30 pm 3D SUPERRESOLUTION MICROSCOPY BY SUPERCRITICAL ANGLE DETECTION. Joran Deschamps , Markus Mund, Jonas Ries 176-P lat 5:45 pm SUPER RESOLUTION IMAGING AND TRACKING OF PROTEIN- PROTEIN INTERACTIONS IN SUB DIFFRACTION CELLULAR SPACE. Zhen Liu , Dong Xing, Qian Peter Su, Yun Zhu, Jiamei Zhang, Xinyu Kong, Boxin Xue, Sheng Wang, Hao Sun, Yile Tao, Yujie Sun

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S A T U R D A Y U N D A Y

4:00 pm –6:00 pm , R oom 307/308 Platform TRP Channels

Co-Chairs Elenora Zakharian, University of Illinois College of Medicine Jie Zheng, University of California, Davis 177-Plat 4:00 pm

SURFACE CHARACTERIZATION AND MEMBRANE INTERAC- TION OF DOUBLE-KNOT TOXIN, AN ACTIVATOR OF TRPV1 CHANNELS. Chanhyung Bae , Andres Jara-Oseguera, Dmitriy V. Krepkiy, Jaeha Ryu, Jae Il Kim, Kenton J. Swartz

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Biophysical Society 59 th Annual Meeting, Baltimore, Maryland