Biophysical Society 59th Annual Meeting Program Guide

234-P os B oard B14 DETERMINANTS OF DOMAIN SWAPPING IN

Protein Structure and Conformation I (Boards B1-B27) 221-P os B oard B1 CHASING UNFOLDING INTERMEDIATES OF IG LIGHT CHAINS WITH RESIDUAL STRUCTURES THAT COULD FIT IN AN AMYLOID CORE. Gilberto Valdes-Garcia , Cesar Millan-Pacheco, Nina Pastor 222-P os B oard B2 international travel awardee BACKBONE DYNAMICS MODULATES THE AMYLOIDOGENIC PROPENSITY OF TRANSTHYRETIN THROUGH NON-NATIVE INTERMEDIATES. Aritra Bej , Jitendra K. Das, Shyam S. Mall, Sujoy Mukherjee 223-P os B oard B3 SELF-REPLICATION OF TRANSTHYRETIN AMYLOID AGGREGATES FROM NATIVE TETRAMERS IN VITRO. Mentor Mulaj , Tatiana Miti, Martin Muschol 224-P os B oard B4 SAS PROFILE CORRELATIONS REVEAL THE HIERARCHICAL NATURE OF SAS DATA AND SUGGEST NEW SCORING STRATEGIES. Michael Nilges , Yannick G. Spill 225-P os B oard B5 COMPUTATIONAL MODELING OF BETA-FIBRILS. Hamed Tabatabaei Ghomi , Elizabeth M. Topp, Markus M. Lill 226-P os B oard B6 THE RESVERATROL DERIVATIVE PICEATANNOL ALTERS THE CONFORMATION OF ALZHEIMER’S DISEASE ASSOCIATED A β PROTEIN AGGREGATES. Yiying Wang , Melissa A. Moss 227-P os B oard B7 EFFECT OF HYDROPHOBIC RESIDUES ON INTERFACIAL FIBRILLIZATION KINETICS. Samantha McBride , Chris Tilger, Amir Hirsa 228-P os B oard B8 AGGREGATION PROPENSITY OF PRION IS KINETICALLY CONTROLLED BY INTRAMOLECULAR DIFFUSION OF PROTEIN CHAIN. Kinshuk R. Srivastava , Lisa J. Lapidus 229-P os B oard B9 PROBING TEMPERATURE DEPENDENT CONFORMATION CHANGE OF CALMODULIN PROTEIN USING MOLECULAR DYNAMICS SIMULATIONS. Sunita Negi 230-P os B oard B10 UNDERSTANDING FORCE-FIELD BIAS IN PIN1WW. Alexandra Iuga 231-P os B oard B11 “PUSH AND PULL” HYPOTHESIS TO UNIFY THE PHYSICAL AND CHEMICAL UNFOLDING OF PROTEINS. Guilherme A. de Oliveira , Jerson L. Silva 232-P os B oard B12 PROBE THE HEME IRON LIGAND AND CONFORMATIONAL CHANGE OF MISFOLDED STATES OF CYTOCHROME C THROUGH EPR SPECTROSCOPY. Qing Huang , Zhigang Ke, Guohua Yao, Shanshan Ma, Jonathan Soffer 233-P os B oard B13 CONSTANT PH SIMULATIONS WITH THE DOUBLE RESERVOIR PH REPLICA EXCHANGE. Ana Damjanovic , Benjamin T. Miller, Asim Okur, Bertrand Garcia-Moreno, Bernard R. Brooks

STAPHYLOCOCCAL NUCLEASE. Meredith Peck , Ilaria Caturegli, Jamie L. Schlessman, Aaron Robinson, Bertrand Garcia-Moreno E. 235-P os B oard B15 MOLECULAR BASIS OF TETRAMERIZATION AND PH- GATING IN THE KCSA POTASSIUM CHANNEL CYTOPLASMIC DOMAIN. Guy Kamnesky, Orel Hirschhorn, Hadassa Shaked, Jingfei Chen, Lishan Yao, Jordan H. Chill 236-P os B oard B16 CHARACTERIZING A NEW METAL BINDING SITE IN S100B. Zephan Melville , Kristen Varney, Michael Cavalier, Sean Stowe, Dylan Weber, Eric Toth, David Weber 237-P os B oard B17 NMR CHARACTERIZATION OF AN UNUSUAL 37 KDA EPIMERIZATION DOMAIN OF YERSINABACTIN SYNTHETASE. Scott R. Nichols , Dominique P. Frueh 238-P os B oard B18 FIBRINOGEN HYDRODYNAMIC PROPERTIES FROM NMR- DIFFUSION STUDIES. Rustem I. Litvinov , Bulat Z. Idiyatullin, Dilyafruz R. Bakirova, Dzhigangir A. Faizullin, Rauf H. Kurbanov, John W. Weisel, Yuriy F. Zuev 239-P os B oard B19 SITE-RESOLVED MEASUREMENTS OF PROTEIN HYDRATION DYNAMICS. Bryan S. Marques , Christine Jorge, Nathaniel V. Nucci, Bertrand E. Garcia-Moreno, A. Joshua Wand 240-P os B oard B20 INTERNAL CAVITIES AND THEIR ROLE AS DETERMINANTS OF PRESSURE UNFOLDING OF PROTEINS. Jose A. Caro , Mariano Dellarole, Martin Fossat, Jamie L. Schlessman, Christian Roumestand, Catherine A. Royer, Bertrand Garcia-Moreno E 241-P os B oard B21 CRYSTAL STRUCTURES OF STREPTOCOCCUS PYOGENES CAS2 PROTEIN AT VARIOUS PH CONDITIONS. Ugeene Jeong 242-P os B oard B22 CRYSTAL STRUCTURES OF STREPTOCOCCUS PYOGENES AND XANTHOMONAS ORYZAE CAS5D PROTEINS. Donghyun Ka , Euiyoung Bae 243-P os B oard B23 UNDERSTANDING STRUCTURAL AND DYNAMIC EFFECTS INDUCED BY KEY COMPONENTS OF THE HCV POLYMERASE REPLICATION COMPLEX. Ester Sesmero , Ian F. Thorpe 244-P os B oard B24 MODELING MACROMOLECULAR BODIES USING 3D MEDIAL AXIS TRANSFORMS AND NORMAL MODE ANALYSIS. Lance Edens, Adam Goler, Suhyun Yoon, James A. Brozik, David J. Keller 245-P os B oard B25 SIMULATING PROTEIN AND NUCLEIC ACID DYNAMICS ON THE MICROSECOND TO MILLISECOND TIMESCALE. Hai Nguyen , James Maier, He Huang, Victoria Perrone, Alberto Perez, Carlos Simmerling 246-P os B oard B26 education travel awardee ENVIRONMENTAL AND MUTATION EFFECTS ON THE FOLDING AND DNA-BINDING OF THE PRIMARY DNA RECOGNITION SUBDOMAIN OF SLEEPING BEAUTY TRANSPOSASE. Gage Leighton , Tatiana Konnova, Irina Nesmelova

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Biophysical Society 59 th Annual Meeting, Baltimore, Maryland