Biophysical Society 59th Annual Meeting Program Guide

470-P os B oard B250 BIOINFORMATIC METHODS FOR THE RAPID IDENTIFICATION OF THERMOSTABILIZING MUTANTS. David B. Sauer , Nathan K. Karpowich, Da-Neng Wang 471-P os B oard B251 INTERACTION OF THE PHAGE ENDOLYSIN PLYC WITH MODEL MEMBRANES. Marilia Barros , Tarek Vennemann, Frank Heinrich, Daniel Nelson, Mathias Lösche 472-P os B oard B252 education travel awardee STRUCTURAL BASIS OF PHOSPHOINOSITIDE (PIP) RECOGNITION BY THE TIRAP PIP-BINDING MOTIF. Xiaolin Zhao , Shuyan Xiao, Sam Berk, Anne M. Brown, David R. Bevan, Geoffrey Armstrong, Daniel G.S. Capelluto 473-P os B oard B253 MECHANISM OF ACTION OF SALT ADAPTATION MUTATIONS IN ARTEMIA FRANCISCANA. Jessica Eastman , Sukanyalakshmi Chebrolu, Pablo Artigas 474-P os B oard B254 DETERMINING OLIGOMERIC ORDER OF A MEMBRANE PROTEIN BY DOUBLE ELECTRON-ELECTRON RESONANCE SPECTROSCOPY. Sergey Milikisiyants, Shenlin Wang, Rachel Munro, Matthew Donohue, Leonid S. Brown, Tatyana I. Smirnova, Vladimir Ladizhansky, Alex I. Smirnov 475-P os B oard B255 NUCLEOTIDE-DEPENDENT MEMBRANE INTERACTION AND DIMERIZATION OF K-RAS4B. Hyunbum Jang , Shaoyong Lu, Mayukh Chakrabarti, Lyuba Khavrutskii, Nadya I. Tarasova, Vadim Gaponenko, Ruth Nussinov 476-P os B oard B256 education travel awardee FORMING THE PSEUDOMONAS AERUGINOSA TRANSLOCON REQUIRES SIMULTANEOUS INCORPORATION OF POPB AND POPD. Kathryn R. Monopoli , Alejandro P. Heuck 477-P os B oard B257 INVESTIGATING THE FUNCTIONAL ROLE OF THE TRANSMEMBRANE SEGMENTS OF YTA10, A SUBUNIT OF THE MAAA PROTEASE, IN MEMBRANE PROTEIN DEGRADATION. Hunsang Lee , Hyun Kim 478-P os B oard B258 OLIGOMER STOICHIOMETRY OF MEMBRANE-BOUND PROTEINS INVOLVED IN A COOPERATIVE PARTITION EQUILIBRIUM: A HOMO-FRET STUDY. Ana M. Melo, A. Fedorov, M. Prieto, Ana Coutinho 479-P os B oard B259 ACTIVATION AND DRUG DESIGN OF A MUSCARINIC G-PROTEIN COUPLED RECEPTOR. Yinglong Miao , J. Andrew McCammon 480-P os B oard B260 ALLOSTERIC EFFECTS OF G-PROTEIN COUPLED RECEPTOR HETEROMERIZATION: RELEVANCE TO PSYCHOSIS. Jason Younkin , Lia Baki, Amr Ellaithy, Diomedes E. Logothetis 481-P os B oard B261 MICROTUBULES SHAPE GPCR SPATIOTEMPORAL MEMBRANE ORGANIZATION AND FUNCTION BY SCAFFOLDING Membrane Receptors and Signal Transduction I (Boards B259-B280)

CORTICAL SIGNALING HUBS. Sandra de Keijzer, Marjolein B.M. Meddens, Samantha L. Schwartz, Peter J. Bosch, Ben Joosten, Johannes S. Kanger, Vinod Subramaniam, Diane S. Lidke, Alessandra Cambi 482-P os B oard B262 LOCALIZATION AND DYNAMICS OF BETA-ADRENERGIC RECEPTOR MEDIATED EGFR TRANSACTIVATION ON MICRO- PATTERNED SURFACES. Peter Lanzerstorfer , Ulrike Müller, Diana Zindel, Otmar Höglinger, Cornelius Krasel, Moritz Bünemann, Julian B oard B263 MEMBRANE CURVATURE REGULATES THE LOCALIZATION OF G PROTEIN COUPLED RECEPTORS AND RAS ISOFORMS. Dimitrios Stamou , Kadla Rosholm, Alexander Damalas, Nikos Hatzakis, Volker Wirth, Karen Martinez, Natascha Leijnse, Lene Oddershede, Poul Martin Bendix, Soren Pedersen 484-P os B oard B264 MOLECULAR SIGNATURES OF G-PROTEIN COUPLED RECEPTORS IN PANCREATIC CANCER USING SUPER- RESOLUTION MICROSCOPY. Raphael Jorand, Ottavia Golfetto, Sunetra Biswas, Steven J. Tobin, Huiying Zhang, Vladana Vukojevic, Tijana Jovanovic-Talisman 485-P os B oard B265 REAL TIME OBSERVATION OF LIGAND BINDING TO A GPCR: CONFORMATIONAL SELECTION GOVERNS THE ABILITY OF RETINALS TO BIND OPSIN. Christopher T. Schafer , David L. Farrens 486-P os B oard B266 NOVEL CHEMICAL BIOLOGY METHODS ILLUMINATE THE FUNCTION OF SINGLE G PROTEIN-COUPLED RECEPTORS. Thomas Huber , Thomas P. Sakmar 487-P os B oard B267 POLYMER-BASED NANODISCS FOR STUDYING STRUCTURE AND DYNAMICS OF G-PROTEIN-COUPLED RECEPTORS. Jana Broecker , Takefumi Morizumi, Wei-Lin Ou, Oliver P. Ernst 488-P os B oard B268 TRACKING VOLTAGE-SENSITIVE MOVEMENTS OF THE M2 MUSCARINIC ACETYLCHOLINE RECEPTOR. Michael F. Priest , Noa Dekel, Ofra Barchad-Avitzur, Yair Ben-Chaim, Francisco Bezanilla 489-P os B oard B269 BETA-ARRESTIN BIASED SIGNALING AT A CLASS A GPCR: MODELING THE ORG27569 INDUCED CB1/BETA-ARRESTIN 1 COMPLEX. Dow P. Hurst , Diane L. Lynch, Derek M. Shore, Michael C. Pitman, Patricia H. Reggio 490-P os B oard B270 MOLECULAR DETERMINANTS AND KINETIC PARAMETERS OF LIGAND BINDING TO G PROTEIN-COUPLED RECEPTORS USING MARKOV STATE MODEL ANALYSIS. Sebastian Schneider , Davide Provasi, Marta Filizola 491-P os B oard B271 LCK CLUSTER DYNAMICS IN LIVE CELLS. Florian Baumgart , Andreas Arnold, Gerhard Schütz 492-P os B oard B272 THE B CELL RECEPTOR DICTATES ITS LOCAL LIPID ENVIRONMENT. Matthew B. Stone , Sarah L. Veatch Weghuber 483-P os

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Biophysical Society 59 th Annual Meeting, Baltimore, Maryland