Biophysical Society 59th Annual Meeting Program Guide

Michel Seigneuret, Jean-Baptiste Fournier, Nicolas Puff, Marino Arroyo, Miglena I. Angelova 3:00 pm coffee break 9-S ubg 3:20 pm PROTEIN SPATIAL DISTRIBUTION DEPENDS ON MEMBRANE CURVATURE. Patricia Bassereau , Coline Prévost, Mijo Simunovic, Sophie Aimon, Gilman Toombes, Andrew Callan-Jones 10-S ubg 3:55 pm STRUCTURAL BASIS OF MEMBRANE CURVATURE RECOGNITION BY THE ALPS MOTIFS. Liza Mouret, Lydie Vamparys, Joachim Moser von Filseck, Patrick Fuchs, Arnaud Bondon, Guillaume Drin 11-S ubg 4:30 pm t . e . thompson award lecture MUSINGS AT MID-CAREER: WHAT IS SO SPECIAL ABOUT OMEGA-3 FATTY ACIDS? Scott Feller 5:10 pm business meeting MORNING SYMPOSIUM: THE MITOCHONDRIAL GENOME N o A bstract 9:00 am SELECTIVE TARGETING OF MTDNA SEQUENCES AND APPLICATIONS TO THERAPY. Carlos Moraes N o A bstract 9:30 am NEW PARADIGMS FOR REGULATION OF HUMAN MITOCHONDRIAL TRANSCRIPTION. Craig Cameron 12-S ubg 10:00 am MITOCHONDRIAL DNA STRESS PRIMES THE ANTIVIRAL INNATE IMMUNE RESPONSE. Phillip West 10:30 am coffee break N o A bstract 11:00 am MTDNA TOPOISOMERASES. Yves Pommier N o A bstract 11:30 am NEW INSIGHTS INTO THE CAUSES OF MITOCHONDRIAL GENOME INSTABILITY. Brett Kaufman AFTERNOON SYMPOSIUM: MITOCHONDRIAL OUTER MEMBRANE TRANSPORT SYSTEMS: STRUCTURE, PROPERTIES, AND PHYSIOLOGICAL IMPLICATIONS 1:45 pm presentation of the young bioenergeticist award 13-S ubg 2:00 pm HIGH RESOLUTION CRYSTAL STRUCTURES OF TRANSLOCATOR PROTEIN 18 KDA (TSPO) REVEAL LIGAND BINDING SITES AND EFFECTS OF A HUMAN SINGLE POLYMORPHISM. Shelagh Ferguson-Miller , Fei Li, Jian Liu, Yi Zheng, Lance Valls, R. Michael Garavito 14-S ubg 2:30 pm TRANSLOCATOR PROTEIN IN MITOCHONDRIAL CHOLESTEROL TRANSPORT AND THE PHARMACOLOGY OF STEROIDOGENESIS. Vassilios Papadopoulos 9:00 am –7:00 pm , R oom 314/315 Subgroup Bioenergetics Subgroup Co-Chairs Jan Hoek and György Hajnóczky, Thomas Jefferson University

Saturday, February 7 8:00 am –1:00 pm , R oom 318 Society of General Physiologists Council Meeting 8:00 am –6:30 pm , C harles S treet L obby Registration/Exhibitor Registration 8:30 am –11:00 am , H ilton B altimore , P eale A-B Joint Council Meeting 9:00 am –5:10 pm , B allroom II Subgroup Membrane Structure and Assembly Subgroup Chair Marjorie Longo, University of California, Davis 1-S ubg 9:00 am PHOSPHATIDYLGLYCEROL ASYMMETRY AND TRANSLOCATION IN LIPID MEMBRANES. John Conboy 2-S ubg 9:35 am CONTROL OF MEMBRANE ASYMMETRY BY P4-ATPASES. Todd R. Graham 3-S ubg 10:10 am COMPUTER SIMULATIONS OF LIPID FLIP-FLOP AND MEMBRANE ASYMMETRY. D. Peter Tieleman 10:45 am coffee break 4-S ubg 11:05 am INVESTIGATING THE MECHANISMS OF NON-RANDOM SPHINGOLIPID ORGANIZATION IN THE PLASMA MEMBRANES OF FIBROBLAST CELLS. Mary L. Kraft , Jessica F. Frisz, Haley A. Klitzing, Robert L. Wilson, Ashley Yeager, Vladimir Lizunov, Joshua J. Zimmerberg, Peter K. Weber 5-S ubg 11:40 am NANOSCALE STRUCTURE AND DYNAMICS OF THE LIQUID ORDERED PHASE. Sodt J. Alexander, Klaus Gawrisch, Richard W. Pastor, Edward R. Lyman 12:15 pm break 6-S ubg 1:15 pm PROBING MEMBRANE PROTEIN SEQUESTRATION AND OLIGOMERIZATION IN POLYMER-TETHERED PHOSPHOLIPID BILAYERS CONTAINING RAFT-MIMICKING LIPID MIXTURES. Christoph Naumann 7-S ubg 1:50 pm PROTEIN CROWDING MODULATES THE SHAPE AND CONTENT OF CURVED MEMBRANES AND COATED VESICLES. Jeanne Stachowiak 8-S ubg 2:25 pm DIRECT MONOLAYER PACKING IMBALANCE AND PHOSPHOLIPID FLIP-FLOP: TWO MECHANISMS OF LOCAL BILAYER DEFORMATION. APPLICATION TO MITOCHONDRIAL CRISTAE OF WILD-TYPE AND CARDIOLIPIN-DEFICIENT MUTANT. Nada Khalifat, Mohammad Rahimi, Anne-Florence Bitbol,

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Biophysical Society 59 th Annual Meeting, Baltimore, Maryland