Biophysical Society 59th Annual Meeting Program Guide

1029-P lat 5:00 pm MAPPING LAC REPRESSOR INTERACTIONS ALONG DNA WITH ULTRA-FAST OPTICAL TWEEZERS. Alessia Tempestini , Carina Monico, Francesco Vanzi, Francesco Saverio Pavone, Marco Capitanio 1030-P lat 5:15 pm DIRECT OBSERVATION OF TALE PROTEIN SEARCH DYNAMICS ALONG DNA. Luke W. Cuculis , Zhanar Abil, Huimin Zhao, Charles M. Schroeder 1031-P lat 5:30 pm DYNAMIC DNA TARGET PROOFREADING IN A CRISPR-CAS SYSTEM. Marius Rutkauskas , Tomas Sinkunas, Maria S. Tikhomirova, Virginijus Siksnys, Ralf Seidel 1032-P lat 5:45 pm SINGLE-MOLECULE IMAGING REVEALS DYNAMICS OF SA1- TRF1 INTERACTIONS ON TELOMERIC DNA. Jiangguo Lin , Haijiang Chen, Parminder Kaur, Wang Miao, Preston Countryman, Changjiang You, Jacob Piehler, Yizhi J. Tao, Susan Smith, Hong Wang 4:00 pm –6:00 pm , R oom 314/315 Platform Molecular, Cellular, and Systems Neuroscience: Experimental Approaches, Modeling, and Tools Co-Chairs ELECTROPHYSIOLOGY-BASED SORTING AND SCREENING WITH NANOWIRE ELECTRODES IN MICROFLUIDIC DEVICES. Daniel L. Gonzales, Daniel G. Vercosa, Andrew M. Bell, Benjamin W. Avants, Jacob T. Robinson 1034-P lat 4:15 pm MECHANICAL SURFACE WAVES ACCOMPANY ACTION POTENTIAL PROPAGATION. Benjamin B. Machta , Ahmed El Hady 1035-P lat 4:30 pm PENETRATION OF ACTION POTENTIALS DURING COLLISION IN THE MEDIAL GIANT AXON OF INVERTEBRATES. Rima Budvytyte , Alfredo Gonzalez-Perez, Lars D. Mosgaard, Soren Nissen, Thomas Heimburg 1036-P lat 4:45 pm DYNAMICS OF GLYCINE RECEPTORS AND THEIR INTERACTIONS WITH GEPHYRIN SCAFFOLDS REVEALED WITH HIGH-DENSITY SINGLE PARTICLE TRACKING AND BAYESIAN INFERENCE. Mohamed El Beheiry , Jean-Baptiste Masson, Charlotte Salvatico, Christian Specht, Antoine Triller, Maxime Dahan 1037-P lat 5:00 pm ROBUST OPTICAL STIMULATION OF NEURONAL ACTIVITY USING FUNCTIONALIZED GOLD NANOPARTICLES. João L. Carvalho-de-Souza , Jeremy S. Treger, Bobo Dang, Stephen Kent, David R. Pepperberg, Francisco Bezanilla Jacob Robinson, Baylor College of Medicine Benjamin Machta, Princeton University 1033-P lat 4:00 pm

1038-P lat 5:15 pm LIGAND FINGERPRINTING IN THE MEMBRANE DYNAMICS OF SINGLE TRKA AND P75NTR NEUROTROPHIN RECEPTORS. Stefano Luin , Laura Marchetti, Fulvio Bonsignore, Fabio Beltram, Antonino Cattaneo 1039-P lat 5:30 pm LOCAL TEMPERATURE EVOLUTION DURING NANOPARTICLE HYPERTHERMIA PROBED BY FLUORESCENCE THERMOMETRY. Rahul Munshi, Idoia Castellanos-Rubio, 5:45 pm NANOMECHANICAL CHARACTERIZATION OF ACTIVE SYNAPSES IN LIVE HIPPOCAMPAL NEURONS. Ju Yang , Roger Lefort, Ozgur Sahin Arnd Pralle 1040-P lat Co-Chairs Juan Perilla, University of Illinois at Urbana-Champaign Steven Poelzing, Virginia Tech 1041-P lat 4:00 pm COMPUTATIONAL STUDIES ON THE CAMP MODULATION OF THE HCN2 CHANNEL. Florentina Tofoleanu , Bernard Brooks 1042-P lat 4:15 pm FROM SMALL TO LARGE TO VERY LARGE: MODELING OF BIOMOLECULAR STRUCTURES IN IMPLICIT SOLVENT. Alexey V. Onufriev 1043-P lat 4:30 pm ACUTE MODULATION OF SODIUM CHANNEL BIOPHYSICAL PROPERTIES USING HIGH-FREQUENCY STIMULATION. Steven Poelzing , Michael Entz, Seth H. Weinberg 1044-P lat 4:45 pm ANALYSIS OF DOMAIN MOVEMENT AND DYNAMICS OF NORWALK VIRUS CAPSID BY MOLECULAR DYNAMICS (ALL- ATOM AND COARSE GRAINED) SIMULATIONS AND NORMAL MODE ANALYSIS. Mahendra B. Thapa , Mark Rance, Jarek Meller 1045-P lat 5:00 pm STUDYING THE GATING MECHANISM OF MAMMALIAN KIR CHANNELS USING IN SILICO MUTATIONS. Eva-Maria Zangerl , Anna Stary-Weinzinger 1046-P lat 5:15 pm MULTISCALE ANALYSIS OF FUNCTIONAL MOTIONS IN F1- ATPASE: FROM PI RELEASE TO ELASTICITY AND FRICTION OF Γ -SUBUNIT ROTATION. Kei-ichi Okazaki , Gerhard Hummer 1047-P lat 5:30 pm ION CHANNEL REGULATION BY LIPID BILAYERS: THEORY & SIMULATION OF DEFORMED MEMBRANES AROUND GRAMICIDIN A. Andrew H. Beaven , Alexander J. Sodt, Olaf S. Andersen, Richard W. Pastor, Wonpil Im 1048-P lat 5:45 pm ATOMISTIC CHARACTERIZATION OF THE HIV CAPSID FROM MOLECULAR DYNAMICS SIMULATIONS. Juan R. Perilla , Klaus Schulten 4:00 pm –6:00 pm , R oom 316/317 Platform Large-scale Molecular Simulations

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Biophysical Society 59 th Annual Meeting, Baltimore, Maryland