AOAC SPIFAN Stakeholder Program Meeting Book (September 10, 2020)

Preliminary Interlaboratory Study

• Highest RSD R observed at lowest chlorate/perchlorate levels • Most laboratories used LC-MS/MS methods

• No obvious biases other than for one laboratory that did not use labeled ISTD • One laboratory used IC-MS – results poor but laboratory attributed this to sample preparation issues and not instrumental analysis • No observed trends based on laboratory experience • Most participants were manufacturers (50 %) or CROs (40 %) - no government laboratories participated • Laboratories expressed a variety of experience and frequency of testing these types of samples

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Follow-Up Interlaboratory Study

• Follow up study being conducted to gather additional data • Looking for more laboratories to participate • Looking for government laboratories to participate • Additional soy ingredient sample to be included • Free to participate; laboratories must pay for sample shipment

Participant Signup (Sep ‘20)

Sample Distribution (Jan ’21)

Results Due (Feb ’21)

Call for participation open through Oct 1 at https://qa.nist.gov/hamqap

Preliminary Data Evaluation (Mar '21)

Final Report (Fall ‘21)

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