2016_Head & Neck COURSE BOOK

Conclusion fractionation  ‐

• Awareness of the fractionation sensitivity of  tumors and normal tissues is critical • Clinical studies and meta‐analysis have shown  that moderately accelerated radiotherapy  improves loco‐regional control H f ti t d RT i l i l • yper rac ona e mproves oco‐reg ona  control and survival • Altered fractionation is thus recommended for  primary radiotherapy of head and neck cancer