September 2015 SPADA Meeting

Devignat Classification

Biovar

Glycerol Nitrate

Arabinose

Comment

+ + + -

+ +

Antiqua

Justinian plague AD 541-544 began in Egypt; 1 st pandemic Black Death 1347- 1351 from central Asia to Europe; 2 nd pandemic Yunnan China 1855 global spread including Americas; 3 rd pandemic New biovar described in China; virulent for rodents but avirulent for humans

Mediaevalis

-

+

+

Orientalis

+ -

-

Microtus

Russian Classification

Y. pestis subspecies

Rhamnose Mellobiose Arabinose Devignat Classificati on a

pPla b

Virulence in guinea pigs c

pestis (epidemic)

-

-

+

A, M, O +

+

altaica

+ + + + +

+ + + + +

-

M +

- - - - -

caucasica hissarica ulegeica talassica

+

A

-

-

M + M + M +

+

-