March 17, 2015-SP

3/17/2015

A high throughput quantitative and confirmatory method for the analysis of monofluoracetate in nutritional products by liquid chromatography-mass spectrometry Nick Cellar Stefan Ehling and Murali Reddy , ,

March, 2015

Proprietaryand confidential — do not distribute © 2015 Abbott Laboratories

MONOFLUOROACETATE SODIUM 

• Molecular Formula: C 2 Average mass: 100.024 Da • Sodium fluoroacetate is a fluffy white material at room temperature, which forms colorless solutions with water and is normally odorless. • Used to control wild dogs, feral pigs, foxes, cats, possums and rabbits in New Zealand and Australia • Occurs naturally in a number of native plant species including Acacia georginae (Georgina gidgee) and members of the Gastrolobium and Oxylobium genera. • Fluoroacetate interferes with the citric acid (Krebs) cycle. Known toxicity to carnivores (dogs)/herbivores (cattle)/omnivores (pigs) • The LD50 value for cattle is 0.4 mg/Kg body weight H 2 FNaO 2

Proprietaryand confidential — do not distribute © 2015 Abbott Laboratories

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March17,2015

MFA‐AOAC,2015 

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