March 17, 2015-SP

3/17/2015

MDL SPIKE CHROMATOGRAM (0.01 ug/g POWDER)

03121510 Smooth(Mn,2x2) QC1

MRMof 2 channels,ES- 212 > 182

MFA-2NPH 4.05

3.895e+004

100

4 74 .

6.59

6.66

4.81

%

6.27

6.90

3.16 2.83 3.35

6.21 5.48 4.91

4.22

0

min

03121510 Smooth(Mn,2x2) QC1

MRMof 2 channels,ES- 216 > 186

MFA-2NPH_IS 4.04

3.198e+005

100

%

0

min 0.50 1.00 1.50 2.00 2.50 3.00 3.50 4.00 4.50 5.00 5.50 6.00 6.50 7.00

Proprietaryand confidential — do not distribute © 2015 Abbott Laboratories

MFA‐AOAC, 2015 

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“DERIVATIZATION” METHOD PERFORMANCE DATA (3 DAYS ACCURACY/PRECISION DATA) 

Sample In powder (ug/g) In RTF liquid (ug/g) QC-MDL 0.01 0.001 QC-Low 0.025 0.0025 QC-Med 0.1 0.01 QC-High 0.5 0.05

MDL Calculation

t-value, 99% CI, (N-1) = 8 degrees of freedom

2.896

0.56

SD

LOD

1.4 ppb

Proprietaryand confidential — do not distribute © 2015 Abbott Laboratories

MFA‐AOAC, 2015 

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