2019 Vet Drug Residues ERP - Review Book

AOAC SMPR ERPs - 2019 METHOD REVIEW FORM

Submission Date

2019-08-31 11:55:10

Name

TOMASZ TUZIMSKI

E-mail

tomasz.tuzimski@umlub.pl

Organization

Medical University of Lublin, Poland

Title of Method

Veterinary Drug Residues submitted by Thierry Delatour

AOAC Candidate Method Number (e.g. ALN-01)

VD4S154

Applicable SMPR

AOAC SMPR® 2018.010

I. Summary of the Method

The proposed method described determination 154 drug residues (such as 107 typical veterinary drugs, 23 Beta-Lactam residues, 14 aminoglycosides, 5 compounds from tetracyclines group (plus related epimers) in a broad range of food matrices including milk-based, meat-based, and fish-based ingredients, and their products by liquid chromatography - triple quadrupole tandem mass spectrometry (LC-MS/MS). The developed method was evaluated following the definitions of Standard Method Performance Requirements (SMPRs®) for Screening and Identification Method for Regulated Veterinary Drug Residues in Food (AOAC SMPR® 2018.010) with respect to Limit of Detection (LOD) and the Limit of Quantitation (LOQ), Linearity, Repeatability, Reproducibility, Recovery.

II. Review of the Method Only 1. Does the applicability of the method support the applicability of the SMPR? If not, please explain what is missing. 2. Does the analytical technique(s) used in the method meet the SMPR? If not, please specify how it differs from what is stated in the SMPR. 3. Are the definitions specified in the SMPR used and applied appropriately in the method? If no, please indicate how the terms are used.

YES: The applicability of the method is adequate to the applicability of the SMPR.

YES: The analytical techniques in the method are adequate and meet the SMPR.

YES: Definitions, which are specified in the SMPR, were listed in the description, also were applied appropriately in the method.