Lower GI 2016

UNICANCER ACCORD 16 phase II trial Inclusion: T2 >3cm -T4 or N+ M0, HIV neg;

Cetuximab 400 mg/m², then weekly 250 mg/m²

Cisplatin 80 mg/m²/d1

5-FU 800/m²/d1-3

2 weeks break

Boost 20 Gy in 10 #

RT: 45 Gy in 25 # (IMRT preferred)