Lower GI 2016

MRC-CR07 – Local Recurrences

Local Recurrence Rate (3y)

TME- Quality

RT + TME

TME

HR

N

„Poor “ Defects to Muscularis propria „Moderat “ Intra-mesorectal excision

154 (13%)

10% 16% 2.0

398 (34%)

4%

10% 2.8

„Optimal “ Mesorectal excision

604 (52%)

1%

7% 4.5

Sebaq-Montefiori D. et al., Lancet 2009 Similar results: Dutch TME Trial, Kapiteijn E, N Engl J Med 2001