Lower GI 2016

Polish Trial

5x5 Gy CRT

P value

Acute Tox (Grade 3-4, %)

3

18 <.001

pCR (%)

1

16 <.001

CRM + (%)

13

4 0.02

61

58 n.s.

Sphincter Preservation (%)

Local Recurrences (4y, %)

11

16 n.s.

Overall Survival (4y, %)

67

66 n.s.

Med. F/U: 48 months

Late Tox (Grade 3-4, %)

10

7

n.s.

Bujko et al., Radiother Oncol 2004 Buiko et al., Br J Surg 2006 Pietrzak et al. Radiother Oncol 2007