Lower GI 2016

Stockholm III Trial

Inclusion Criteria: clinically resectable RC < 15 cm from AV

1 Week

5x5 Gy

TME

4 to 8 Weeks

R

5x5 Gy

TME

4 to 8 Weeks

25 x 2 Gy

TME

Primary endpoint: Time to local recurrence, 840 pts to show equality (15% @ 5y, power 80%) Secondary: acute, late tox, QoL, overall survival