Lower GI 2016

Stockholm III Trial

5x5 Gy immediate TME

5x5 Gy delayed TME

25x2 Gy delayed TME

First interim analysis after 300 pts (1998-2005)

Number of pts

118

120

65

Severe RT-induced Tox (hospital admission, %) Postop. Complications (%) Reoperations (%) Anastomotic leak (%)

0

4.2

5

47 10 13

40 11 11

32 5 4

Petterssons et al., Br J Surg 2010