Lower GI 2016

Conclusions (I) What have we learned?

• Sequence RT, Chemo, S matters (CAO/ARO/AIO-94)

• Synergy RT – 5-FU Chemo (FFCD 9303, EORTC 22921)

• RT - optimized S complementary (Dutch Trial, MRC CR07)

• Interval between RT + S matters (TIMING; Stockholm III)

• Compliance RT + Chemo matters (CAO/ARO/AIO-04)