Lower GI 2016

Pre- vs post-operative chemoradiation CAO/ARO/AIO-94

Locoregional Recurrences

0.3

Acute G3/4 adverse events 27% vs 40% (p=0.001)

P =0.006

0.2

Long-term G3/4

adverse events 14% vs 24% (p=0.01)

13%

Post

0.1

6%

Pre

There is a standard for chemoradiation

0.0

0

60

12

24

36

48

Months

Sauer R. et al., N Engl J Med 2004;351: 1731-39