The Greater Princeton Area Ask the Doctor Spring Issue March/April 2018

Concerned About Your Memory?

• Feelings of sad • Guilt • Emptiness • Worthlessness • Not enjoying ev • Hopelessness

Register for a FREECONSULTATION with leading Princeton Physicians

• Trouble concen • Restless, irritabl You may be interested to know t Princeton Medical Institute is conducting a clinical r of an investigational drug aimed at relieving the sy of Depression in children ages 12-17. » Study drug » Study related examinations » Lab » Evaluation by a board certified Psychiatrist Qualified participants will receive at no co We offer FREE consultations, memory screens, PET scans, MRIs, and CAT scans to qualified patients.

Dr. Jeffrey Apter isMedical Director at PrincetonMedical Institute, Senior attending Physician at theUniversity Medical Center of Princeton, and aMember of the Scientific Advisory Board of theNew Jersey Alzheimer Association. Please call to schedule your FREE consultation.

TO SEE IF YOUR CHILD IS ELIGIBLE TO PARTICIPATE Compensation is available for time and

PRINCETON

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Our Events Are Always FREE andOpen to the Public See our website for details. www.PrincetonMedical I nstitute.com

Where today’s research brings tomorrow's s www.gmin MEDICAL INSTITUTE

609-921-6050 • www.PrincetonMedical I nstitute.com 256 Bunn Drive, Suite 6 • Princeton, NJ 08540 “Where today’s research brings tomorrow’s solutions”

Accepting patients for: Alzheimer’s/memory loss • depression • CRPS • migraine/cluster headaches

What is Phelan-McDermid Syndrome? By Lauren Kolacki

First characterized in 1985, Phelan-McDermid Syndrome (PMS), is a rare neurodevelopmental disorder where there is breakage and rearrangement within the 22nd chromosome. Chromosomes are found in the nucleus of all body cells and are responsible for carrying genetic information for the growth and development of everyone. The deletion of 22q13, results in an inversion that depresses cognitive, intellectual, and physical growth which alters speech, motor skills, and muscle tone. Phelan-McDermid Syndrome is usually first characterized by hypotonia, which is low muscle tone in a newborn, but is also discovered when children have a lack of developmental milestones such as; rolling over, sitting up, walking, or talking on time. Those who are diagnosed with PMSmay possess behavioral abnormalities that mimic autism. These include, animosity towards changes in routine, sensory sensitivity, repetitiveness, chewing, delayed speech, etc.

Unfortunately, there is no specific treatment for this syndrome. Each symptom can be treated specifically with the help of pediatricians, neurologists, nephrologists, gastroenterologists, immunologists, orthopedists, physical or occupational therapists, and speech/language pathologists. It is important to spread awareness of this rare disease to provide support for those experiencing it and to educate those who will be affected in the future. If you have a child with these symptoms, please speak to your physician.

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ASK THE DOCTOR September/October 2016

MARCH/APRIL 2018