NCCN VERSION 2 2015

NCCN Guidelines Version 2.2015 Breast Cancer

NCCN Guidelines Index Breast Cancer Table of Contents Discussion

randomised trial. The Lancet 2012. Available at: http://linkinghub.elsevier.com/retrieve/pii/S0140673612619631 . 266. Gray R, Rea D, Handley K, et al. aTTom (adjuvant Tamoxifen—To offer more?): Randomized trial of 10 versus 5 years of adjuvant tamoxifen among 6,934 women with estrogen receptor-positive (ER+) or ER untested breast cancer—Preliminary results[ abstract]. J Clin Oncol 2008;15_Suppl:Abstract 513. Available at: http://meeting.ascopubs.org/cgi/content/abstract/26/15_suppl/513 . 267. Pritchard KI. Ovarian suppression/ablation in premenopausal ER- positive breast cancer patients. Issues and recommendations. Oncology 268. Puhalla S, Brufsky A, Davidson N. Adjuvant endocrine therapy for premenopausal women with breast cancer. Breast 2009;18 Suppl 3:S122-130. Available at: http://www.ncbi.nlm.nih.gov/pubmed/19914530 . 269. Tan SH, Wolff AC. The role of ovarian ablation in the adjuvant therapy of breast cancer. Curr Oncol Rep 2008;10:27-37. Available at: http://www.ncbi.nlm.nih.gov/pubmed/18366958 . 270. Cuzick J, Ambroisine L, Davidson N, et al. Use of luteinising- hormone-releasing hormone agonists as adjuvant treatment in premenopausal patients with hormone-receptor-positive breast cancer: a meta-analysis of individual patient data from randomised adjuvant (Williston Park) 2009;23:27-33. Available at: http://www.ncbi.nlm.nih.gov/pubmed/19283918 .

272. Ejlertsen B, Mouridsen HT, Jensen MB, et al. Similar efficacy for ovarian ablation compared with cyclophosphamide, methotrexate, and fluorouracil: from a randomized comparison of premenopausal patients with node-positive, hormone receptor-positive breast cancer. J Clin Oncol 2006;24:4956-4962. Available at: http://www.ncbi.nlm.nih.gov/pubmed/17075113 . 273. Goel S, Sharma R, Hamilton A, Beith J. LHRH agonists for adjuvant therapy of early breast cancer in premenopausal women. Cochrane Database Syst Rev 2009:CD004562. Available at: http://www.ncbi.nlm.nih.gov/pubmed/19821328 . 274. Kaufmann M, Jonat W, Blamey R, et al. Survival analyses from the ZEBRA study. goserelin (Zoladex) versus CMF in premenopausal women with node-positive breast cancer. Eur J Cancer 2003;39:1711- 1717. Available at: http://www.ncbi.nlm.nih.gov/pubmed/12888366 . 275. Schmid P, Untch M, Wallwiener D, et al. Cyclophosphamide, methotrexate and fluorouracil (CMF) versus hormonal ablation with leuprorelin acetate as adjuvant treatment of node-positive, premenopausal breast cancer patients: preliminary results of the TABLE-study (Takeda Adjuvant Breast cancer study with Leuprorelin Acetate). Anticancer Res 2002;22:2325-2332. Available at: http://www.ncbi.nlm.nih.gov/pubmed/12174922 . 276. Thomson CS, Twelves CJ, Mallon EA, Leake RE. Adjuvant ovarian ablation vs CMF chemotherapy in premenopausal breast cancer patients: trial update and impact of immunohistochemical assessment of

trials. Lancet 2007;369:1711-1723. Available at: http://www.ncbi.nlm.nih.gov/pubmed/17512856 .

ER status. Breast 2002;11:419-429. Available at: http://www.ncbi.nlm.nih.gov/pubmed/14965706 .

271. Davidson NE, O'Neill AM, Vukov AM, et al. Chemoendocrine therapy for premenopausal women with axillary lymph node-positive, steroid hormone receptor-positive breast cancer: results from INT 0101 (E5188). J Clin Oncol 2005;23:5973-5982. Available at: http://www.ncbi.nlm.nih.gov/pubmed/16087950 .

277. von Minckwitz G, Graf E, Geberth M, et al. CMF versus goserelin as adjuvant therapy for node-negative, hormone-receptor-positive breast cancer in premenopausal patients: a randomised trial (GABG trial IV-A-93). Eur J Cancer 2006;42:1780-1788. Available at: http://www.ncbi.nlm.nih.gov/pubmed/16765589 .

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