NCCN VERSION 2 2015

NCCN Guidelines Version 2.2015 Breast Cancer

NCCN Guidelines Index Breast Cancer Table of Contents Discussion

cancer. Updated results of the Italian tamoxifen anastrozole (ITA) trial. Ann Oncol 2006;17 Suppl 7:10-14. Available at: http://www.ncbi.nlm.nih.gov/pubmed/16760270 . 298. Coombes RC, Hall E, Gibson LJ, et al. A randomized trial of exemestane after two to three years of tamoxifen therapy in postmenopausal women with primary breast cancer. N Engl J Med 2004;350:1081-1092. Available at: http://www.ncbi.nlm.nih.gov/pubmed/15014181 . 299. Jakesz R, Jonat W, Gnant M, et al. Switching of postmenopausal women with endocrine-responsive early breast cancer to anastrozole after 2 years' adjuvant tamoxifen: combined results of ABCSG trial 8 and ARNO 95 trial. Lancet 2005;366:455-462. Available at: http://www.ncbi.nlm.nih.gov/pubmed/16084253 . 300. Jonat W, Gnant M, Boccardo F, et al. Effectiveness of switching from adjuvant tamoxifen to anastrozole in postmenopausal women with hormone-sensitive early-stage breast cancer: a meta-analysis. Lancet Oncol 2006;7:991-996. Available at: http://www.ncbi.nlm.nih.gov/pubmed/17138220 . 301. van de Velde CJ, Rea D, Seynaeve C, et al. Adjuvant tamoxifen and exemestane in early breast cancer (TEAM): a randomised phase 3 302. Goss PE, Ingle JN, Martino S, et al. A randomized trial of letrozole in postmenopausal women after five years of tamoxifen therapy for early-stage breast cancer. N Engl J Med 2003;349:1793-1802. Available at: http://www.ncbi.nlm.nih.gov/pubmed/14551341 . 303. Goss PE, Ingle JN, Pater JL, et al. Late extended adjuvant treatment with letrozole improves outcome in women with early-stage breast cancer who complete 5 years of tamoxifen. J Clin Oncol 2008;26:1948-1955. Available at: http://www.ncbi.nlm.nih.gov/pubmed/18332475 . trial. Lancet 2011;377:321-331. Available at: http://www.ncbi.nlm.nih.gov/pubmed/21247627 .

291. Dowsett M, Cuzick J, Howell A, Jackson I. Pharmacokinetics of anastrozole and tamoxifen alone, and in combination, during adjuvant endocrine therapy for early breast cancer in postmenopausal women: a sub-protocol of the 'Arimidex and tamoxifen alone or in combination' (ATAC) trial. Br J Cancer 2001;85:317-324. Available at: http://www.ncbi.nlm.nih.gov/pubmed/11487258 . 292. Buzdar AU, Guastalla JP, Nabholtz JM, et al. Impact of chemotherapy regimens prior to endocrine therapy: Results from the ATAC (anastrozole and tamoxifen, alone or in combination) trial. Cancer 2006;107:472-480. Available at: http://www.ncbi.nlm.nih.gov/pubmed/16804925 . 293. Mouridsen H, Keshaviah A, Coates AS, et al. Cardiovascular adverse events during adjuvant endocrine therapy for early breast cancer using letrozole or tamoxifen: safety analysis of BIG 1-98 trial. J Clin Oncol 2007;25:5715-5722. Available at: http://www.ncbi.nlm.nih.gov/pubmed/17998546 . 294. Rabaglio M, Sun Z, Price KN, et al. Bone fractures among postmenopausal patients with endocrine-responsive early breast cancer treated with 5 years of letrozole or tamoxifen in the BIG 1-98 trial. Ann Oncol 2009;20:1489-1498. Available at: http://www.ncbi.nlm.nih.gov/pubmed/19474112 . 295. Mouridsen H, Giobbie-Hurder A, Goldhirsch A, et al. Letrozole therapy alone or in sequence with tamoxifen in women with breast cancer. N Engl J Med 2009;361:766-776. Available at: http://www.ncbi.nlm.nih.gov/pubmed/19692688 . 296. Boccardo F, Rubagotti A, Puntoni M, et al. Switching to anastrozole versus continued tamoxifen treatment of early breast cancer: preliminary results of the Italian Tamoxifen Anastrozole Trial. J

Clin Oncol 2005;23:5138-5147. Available at: http://www.ncbi.nlm.nih.gov/pubmed/16009955 .

297. Boccardo F, Rubagotti A, Guglielmini P, et al. Switching to anastrozole versus continued tamoxifen treatment of early breast

Version 2.2015, 03/11/15 © National Comprehensive Cancer Network, Inc. 2015, All rights reserved. The NCCN Guidelines® and this illustration may not be reproduced in any form without the express written permission of NCCN®. MS-88

Made with