NCCN VERSION 2 2015

NCCN Guidelines Version 2.2015 Breast Cancer

NCCN Guidelines Index Breast Cancer Table of Contents Discussion

2012;366:109-119. Available at: http://www.ncbi.nlm.nih.gov/pubmed/22149875 . 483. Ewer M, Baselga J, Clark E, et al. Cardiac tolerability of pertuzumab plus trastuzumab plus docetaxel in patients with HER2- positive metastatic breast cancer in the CLEOPATRA study [abstract]. J Clin Oncol 2012;30 (Suppl_15):Abstract 533. Available at: http://www.asco.org/ASCOv2/Meetings/Abstracts?&vmview=abst_detail _view&confID=114&abstractID=95049 . 484. Cortés J, Baselga J, Im Y, et al. Quality of life assessment in CLEOPATRA, a phase III study combining pertuzumab with trastuzumab and docetaxel in metastatic breast cancer [abstract]. J Clin Oncol 2012 30 (Suppl_15) Abstract 598 Available at: http://www.asco.org/ASCOv2/Meetings/Abstracts?&vmview=abst_detail _view&confID=114&abstractID=95084 . 485. Datko F, D'Andrea G, Dickler M, et al. Phase II study of pertuzumab, trastuzumab, and weekly paclitaxel in patients with metastatic HER2-overexpressing metastatic breast cancer [abstract]. Cancer Research 2012;72:Abstract P5-18-20. Available at: http://cancerres.aacrjournals.org/cgi/content/meeting_abstract/72/24_M eetingAbstracts/P5-18-20 . 486. Paclitaxel, trastuzumab, and pertuzumab in the treatment of metastatic HER2-positive breast cancer (Clinical Trial ID: NCT01276041). Available at: http://clinicaltrials.gov/show/NCT01276041 . . 487. Perez E, Lopez-Vega J, Mastro L, et al. A combination of pertuzumab, trastuzumab, and vinorelbine for first-line treatment of patients with HER2-positive metastatic breast cancer: An open-label, two-cohort, phase II study (VELVET) [abstract]. J Clin Oncol 2012;30 (Suppl_15):Asbtract TPS653. Available at: http://www.asco.org/ASCOv2/Meetings/Abstracts?&vmview=abst_detail _view&confID=114&abstractID=93917 .

and first-line chemotherapy as treatment for patients with metastatic breast cancer (MBC) [abstract]. J Clin Oncol 2010;28(Suppl 15):Abstract 1005. Available at: http://meeting.ascopubs.org/cgi/content/abstract/28/15_suppl/1005 . 477. BRIEFING BOOK, ONCOLOGY DRUGS ADVISORY COMMITTEE MEETING, AVASTIN (Bevacizumab). Genentech, Inc., A Member of the Roche Group; 2010. Available at: http://www.fda.gov/downloads/AdvisoryCommittees/CommitteesMeeting Materials/Drugs/OncologicDrugsAdvisoryCommittee/UCM219228.pdf . 478. Seidman A, Berry DA, Cirrincione C, et al. Randomized phase III trial of weekly compared with every-3-weeks paclitaxel for metastatic breast cancer, with trastuzumab for all HER-2 overexpressors and random assignment to trastuzumab or not in HER-2 nonoverexpressors: final results of Cancer and Leukemia Group B protocol 9840. J Clin Oncol 2008;26:1642-1649. Available at: http://www.ncbi.nlm.nih.gov/pubmed/18375893 . 479. Carlson RW, Moench SJ, Hammond ME, et al. HER2 testing in breast cancer: NCCN Task Force report and recommendations. J Natl Compr Canc Netw 2006;4 Suppl 3:1-22. Available at: http://www.ncbi.nlm.nih.gov/pubmed/16813731 . 480. Roche PC, Suman VJ, Jenkins RB, et al. Concordance between local and central laboratory HER2 testing in the breast intergroup trial N9831. J Natl Cancer Inst 2002;94:855-857. Available at: http://www.ncbi.nlm.nih.gov/pubmed/12048274 . 481. Wolff AC, Hammond MEH, Schwartz JN, et al. American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer. J Clin Oncol 2007;25:118-145. Available at: http://www.ncbi.nlm.nih.gov/pubmed/17159189 . 482. Baselga J, Cortes J, Kim SB, et al. Pertuzumab plus trastuzumab plus docetaxel for metastatic breast cancer. N Engl J Med

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