PracticeUpdate Diabetes March 2019

CONTENTS 3

TOP STORIES 2018 5 The ASCEND Study By Richard E. Pratley MD

EXPERT OPINION 20

Disordered Eating Behaviors in Adolescents With Type 1 Diabetes By Elizabeth A. Doyle DNP, APRN, BC-ADM, CDE

RESEARCH Editor’s picks 6 Type 1 Diabetes Management and Outcomes Comment by William V. Tamborlane MD and Michelle A. Van Name MD 7 Effect of Metformin in Addition to Dietary and Lifestyle Advice for Pregnant Women Who Are Overweight or Obese

12 Incretin-Based Drugs and Risk of Cholangiocarcinoma Among Patients With Type 2 Diabetes Comment by Michael Nauck MD 13 Neurocognitive and Hormonal Correlates of Voluntary Weight Loss in Humans 14 Carbohydrate Quality and Human Health: A Series of Systematic Reviews and Meta-Analyses Comment by Mark A. Pereira PhD 15 Association of Biochemical Hypoglycemia With the Subsequent Risk of a Severe Hypoglycemic Event 16 Maternal Glycemia and Childhood Glucose Metabolism Comment by Christina S. Han MD 17 Risk Factors for Readmission of Inpatients With Diabetes Comment by Enrico Cagliero MD 17 A Dose–Response Relationship Between Insulin Glargine 100 Units/mL and Glycemic Control 18 Adiposity and Risk of Decline in Glomerular Filtration Rate Comment by F. Perry Wilson MD, MSCE

21 Effects of Dapagliflozin on Circulating Markers of Phosphate Homeostasis By Simeon I. Taylor MD, PhD 22 Management of Hyperglycemia in Type 2 Diabetes, 2018: Consensus Report by ADA and EASD By Silvio E. Inzucchi MD

8 Change in Albuminuria as a Surrogate

Endpoint for Progression of Kidney Disease Comment by Keith C. Norris MD, PhD

9 Analysis of HbA1c as a Risk Factor for Coronary Artery Disease 10 Excess Risk of Hospitalization for Heart Failure Among People With Type 2 Diabetes Comment by Kenneth W. Mahaffey MD 11 Decreasing Cumulative Incidence of End- Stage Renal Disease in Young Patients With Type 1 Diabetes in Sweden Comment by Neera K. Dahl MD, PhD

19 Impact of Birth Weight on Metabolic Syndrome in Adolescents Comment by Nicola Santoro MD, PhD

VOL. 3 • NO. 1 • 2019