Basic Clinical Radiobiology 2017

Combined chemo- and radiotherapy treatment

• Spatial co-operation (e.g. breast carcinoma) • Independent cell kill (e.g. Hodgkin lymphoma) • Interaction (e.g. H&N, cervix, NSCLC) • “diluted” toxicity (e.g. Hodgkin lymphoma)

ESTRO 2017

H&N SCC: MACH-NC

ESTRO 2017

Pignon et al., Lancet 355: 949-955, 2000