Basic Clinical Radiobiology 2017

Changes in consequential late effects Repopulation – clinical observations EORTC 22851 - Mucositis Gr. 3+4

AF: 72 Gy / 45 F / 5 wk CF: 70 Gy / 35 F / 7 wk

14

12

Gr. 3 mucosal late effects - deep necrosis - edema/tracheostomy

10

p=0.011

8

6

4

Fraction of patients [%]

2

0

data from: Horiot et al., RTO 44, 1997, 111-121

ESTRO BCR Course / NT overall treatment time – W. Dörr