Basic Clinical Radiobiology 2017

Repopulation: Mechanisms

100

Observation 1: compensation of dose

complete compensation

10

incomplete compensation

1

no compen- sation

0.1

SF 2

=0.5-0.6

net stem cell production

0.01

0.001

0.0001

Relative stem cell number [%]

0

5

10

15

20

Overall treatment time [days]

ESTRO BCR Course / NT overall treatment time – W. Dörr