Review Team (February 2016)

Bio-03 (February 2016) FOR ERP USE ONLY DO NOT DISTRIBUTE

Table 2. Accuracy – spike recovery.

Spike Recovery

Level 2 (~150% for placebo, ~100% for fortified)

Nr. replicates (n)

Level 1 (~50%)

Native level (mcg/100g reconstituted)

Product

SPIFAN Code

Avg (%) n=3

RSD (%)

Avg (%) n=3

RSD (%)

Child Formula Powder, placebo Adult Nutritional RTF High Protein, placebo Adult Nutritional RTF High Fat, placebo Infant Formula Powder Partially Hydrolyzed Soy Based

00847RF00

6

Not detected

103

3.2

105

1.5

00821RF00

6

Not detected

102

1.6

103

1.5

00820RF00

6

Not detected

102

2.2

104

1.7

410457651Z

6

4.43

105

4.2

101

4.2

Adult Nutritional Powder Low Fat

00859RF00 00866RF00

6 6

31.9 21.6

111 109

2.9 2.8

102 104

1.8 1.7

Child Formula Powder

Infant Elemental Powder

00795RF00

6

10.7

106

2.8

95.1

3.0

Infant Formula Powder FOS/GOS Based Infant Formula Powder Milk Based Adult Nutritional RTF High Protein Adult Nutritional RTF High Fat

50350017W1

6

1.66

105

6.4

99.9

7.2

K16NTAV

6

5.11

104

6.1

103

4.6

00730RF00

6

56.8

109

1.6

102

0.8

00729RF00

6

76.2

109

2.4

101

0.7

Table 3. Accuracy – recovery of SRM 1849a.

SRM Product

Code

Reference value

Measured value

Recovery vs CoA

(mg/kg powder)

(mg/kg powder)

%

1.969 2.067 2.081 2.023 2.047 1.971 2.013 1.987 1.995

99

104 105 102 103 101 100 100 99

1849a

CLC-10b

1.99