Statistics Meeting Book (April 18, 2018)

AOAC INTERNATIONAL COMMITTEE ON STATISTICS

Draft Meeting Agenda Wednesday, April 18 th , 2018 Meeting Start Time: 10:30AM (Eastern US) Chair: Sidney Sudberg (Alkemist Labs) ______________________________________________________________________________ ( Need member to volunteer to take the minutes )

I. WELCOME & INTRODUCTION (Sudberg – 10:30AM‐10:40AM) *

Sidney Sudberg will call the meeting to order, welcome and introduce the members of Statistics Committee. Members will review the AOAC policy documents and vote on the draft meeting agenda.

II. REVIEW OF MEETING AGENDA & MINUTES (All – 10:40AM-10:45AM) * The members of the Statistics Committee will review and vote on the February 14 th , 2018 meeting minutes and the February 14 th , 2018 meeting agenda.

III. CURRENT METHOD CONFORMITY ASSESSMENT PROJECTS (All– 10:45AM-11:05AM)

Progress updates a. Statistics for Microbiology Methods Validation - Paul Wehling & Robert LaBudde (Leads) 1. Progress for Internal Validation Plan a. Robert LaBudde? b. Paul Wehling

Volunteers: 1. Caryn Thompson

4. Hilde Skår Norli 5. Sidney Sudberg

2. Qian Graves 3. Jane Weitzel

b. Changes to Appendix J (in progress) - Paul Wehling & Robert LaBudde (Leads) 1. Quantitative methods need changes (performed during &/or after validation) a. Candidate minus Reference b. New method of calculating the CI for the paired dPod c. Use of Z (n) vs. t (n-1) d. Removal of reference to Welch/Satterthwaite t-test? e. Chi-Square Test Calculator (Robert/Paul) http://lcfltd.com/AOAC/aoac-binary-v2-5.xlsx i. To be discussed with Appendix J changes c. Statistics Committee’s Terms of Reference (ToR) Update – All, ToR Subcommittee 1. Latest version – v8 has been approved by OMB a. Sent to Committee on Statistics for your reading pleasure b. Board of Directors to vote in June

*Requires a vote

version 2

Draft meeting agenda is subject to change without notice2