Conditions (Professional)

PROFESSIONAL

health conditions

Allergic Rhinitis

Professional Monograph

Overview

 An allergic reaction is an inappropriate immune response to an otherwise harmless substance.  Allergens are low molecular weight proteins absorbed into the body through the skin and mucous membranes, respiratory tract, or gastrointestinal tract from environmental, chemical, or food-based sources.  The immune system recognizes the allergen as antigenic and a hypersensitivity reaction follows.

Allergic Rhinitis

 Allergic rhinitis is an immunoglobulin E (IgE) mediated reaction that causes the release of inflammatory compounds in mucous membranes (including the nose, eyes, eustachian tube, sinuses, middle ear and pharynx) when an individual with a sensitized immune system inhales an allergen, such as pollen, dust, mold, or pet dander.  The allergen triggers production of IgE, which binds to mast cells and basophils in the nasal mucosa.  When circulating antigens contact IgE antibodies attached to the mast cells, they trigger the degranulation and release of inflammatory mediators that produce the symptoms of allergic rhinitis.

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